Photodynamic therapy. Biology and clinical application

S. M. Keller

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations


PDT appears capable of treating small, superficial, endoluminal tumors. As the therapeutic light penetration currently goes no further than 1 cm, bulky neoplasms will remain resistant to this form of therapy. Second-generation photosensitizers that are activated by light wavelengths with greater tissue penetration are under development. Similarly, solid-state lasers that require minimal maintenance and facilities are becoming available. Randomized trials comparing PDT with laser thermal ablation are underway. PDT will likely find a niche in the treatment of superficial tumors.

Original languageEnglish (US)
Pages (from-to)121-137
Number of pages17
JournalChest Surgery Clinics of North America
Issue number1
StatePublished - Jan 1 1995

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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