Persistent psychosis from toluene exposure: More likely coincidence than cause: A review of our experience and the literature

Herbert H. Schaumburg, Larry Wade, David Masur

Research output: Contribution to journalArticle

Abstract

Inhalant abuse of toluene is frequently accompanied by visual and auditory hallucinations that cease at varying intervals following withdrawal. One study of institutionalized abusers describes persistent hallucinations despite abstinence, with evolution into a "schizophreniform" psychosis. It is suggested that occupational exposure to toluene can have a similar outcome. Taken in concert with the credible neurological literature, our considerable experience with more than 30 cases of toluene abuse, 15 of toluene solvent mixture neurotoxicity, and of many with considerable workplace exposure indicates the combination of persistent psychosis and toluene inhalation does rarely occur. However, it is the chance coincidence of two relatively common conditions, toluene encephalopathy and underlying schizophrenia.

Original languageEnglish (US)
Pages (from-to)277-280
Number of pages4
JournalCurrent Psychiatry Reviews
Volume3
Issue number4
DOIs
StatePublished - Nov 2007

Fingerprint

Toluene
Psychotic Disorders
Hallucinations
Inhalant Abuse
Brain Diseases
Occupational Exposure
Workplace
Inhalation
Schizophrenia

Keywords

  • Abuse
  • Hallucination
  • Psychosis
  • Schizophrenia
  • Schizophreniform
  • Toluene

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Persistent psychosis from toluene exposure : More likely coincidence than cause: A review of our experience and the literature. / Schaumburg, Herbert H.; Wade, Larry; Masur, David.

In: Current Psychiatry Reviews, Vol. 3, No. 4, 11.2007, p. 277-280.

Research output: Contribution to journalArticle

@article{256ab577845140a8b286a0e35045855f,
title = "Persistent psychosis from toluene exposure: More likely coincidence than cause: A review of our experience and the literature",
abstract = "Inhalant abuse of toluene is frequently accompanied by visual and auditory hallucinations that cease at varying intervals following withdrawal. One study of institutionalized abusers describes persistent hallucinations despite abstinence, with evolution into a {"}schizophreniform{"} psychosis. It is suggested that occupational exposure to toluene can have a similar outcome. Taken in concert with the credible neurological literature, our considerable experience with more than 30 cases of toluene abuse, 15 of toluene solvent mixture neurotoxicity, and of many with considerable workplace exposure indicates the combination of persistent psychosis and toluene inhalation does rarely occur. However, it is the chance coincidence of two relatively common conditions, toluene encephalopathy and underlying schizophrenia.",
keywords = "Abuse, Hallucination, Psychosis, Schizophrenia, Schizophreniform, Toluene",
author = "Schaumburg, {Herbert H.} and Larry Wade and David Masur",
year = "2007",
month = "11",
doi = "10.2174/157340007782408842",
language = "English (US)",
volume = "3",
pages = "277--280",
journal = "Current Psychiatry Reviews",
issn = "1573-4005",
publisher = "Bentham Science Publishers B.V.",
number = "4",

}

TY - JOUR

T1 - Persistent psychosis from toluene exposure

T2 - More likely coincidence than cause: A review of our experience and the literature

AU - Schaumburg, Herbert H.

AU - Wade, Larry

AU - Masur, David

PY - 2007/11

Y1 - 2007/11

N2 - Inhalant abuse of toluene is frequently accompanied by visual and auditory hallucinations that cease at varying intervals following withdrawal. One study of institutionalized abusers describes persistent hallucinations despite abstinence, with evolution into a "schizophreniform" psychosis. It is suggested that occupational exposure to toluene can have a similar outcome. Taken in concert with the credible neurological literature, our considerable experience with more than 30 cases of toluene abuse, 15 of toluene solvent mixture neurotoxicity, and of many with considerable workplace exposure indicates the combination of persistent psychosis and toluene inhalation does rarely occur. However, it is the chance coincidence of two relatively common conditions, toluene encephalopathy and underlying schizophrenia.

AB - Inhalant abuse of toluene is frequently accompanied by visual and auditory hallucinations that cease at varying intervals following withdrawal. One study of institutionalized abusers describes persistent hallucinations despite abstinence, with evolution into a "schizophreniform" psychosis. It is suggested that occupational exposure to toluene can have a similar outcome. Taken in concert with the credible neurological literature, our considerable experience with more than 30 cases of toluene abuse, 15 of toluene solvent mixture neurotoxicity, and of many with considerable workplace exposure indicates the combination of persistent psychosis and toluene inhalation does rarely occur. However, it is the chance coincidence of two relatively common conditions, toluene encephalopathy and underlying schizophrenia.

KW - Abuse

KW - Hallucination

KW - Psychosis

KW - Schizophrenia

KW - Schizophreniform

KW - Toluene

UR - http://www.scopus.com/inward/record.url?scp=36248998965&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=36248998965&partnerID=8YFLogxK

U2 - 10.2174/157340007782408842

DO - 10.2174/157340007782408842

M3 - Article

AN - SCOPUS:36248998965

VL - 3

SP - 277

EP - 280

JO - Current Psychiatry Reviews

JF - Current Psychiatry Reviews

SN - 1573-4005

IS - 4

ER -