Perinatal hemorrhage complicating neonatal hepatoblastoma

Case report

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Hepatoblastoma is the most common malignant liver tumor of infancy and presents most frequently at a median age of 18 months. Presentation in the neonatal period is rare, and there are very few reports of an antenatal diagnosis of hepatoblastoma. We recently encountered a neonate who presented with hemoperitoneum after rupture of a congenital hepatoblastoma during vaginal delivery. After successful right hepatectomy and adjuvant cis-platinum-based chemotherapy, the child is doing well. We draw attention to rarity of this condition and difficulty in definitively establishing a diagnosis both in the antenatal and neonatal periods and discuss the management dilemmas in congenital presentations of hepatoblastoma.

Original languageEnglish (US)
JournalJournal of Pediatric Surgery
Volume47
Issue number10
DOIs
StatePublished - Oct 2012

Fingerprint

Hepatoblastoma
Hemorrhage
Hemoperitoneum
Hepatectomy
Prenatal Diagnosis
Cisplatin
Rupture
Newborn Infant
Drug Therapy
Liver
Neoplasms

Keywords

  • Antenatal screening
  • Congenital hepatoblastoma
  • Hemoperitoneum

ASJC Scopus subject areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health

Cite this

Perinatal hemorrhage complicating neonatal hepatoblastoma : Case report. / Lai, May; Burjonrappa, Sathyaprasad.

In: Journal of Pediatric Surgery, Vol. 47, No. 10, 10.2012.

Research output: Contribution to journalArticle

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AB - Hepatoblastoma is the most common malignant liver tumor of infancy and presents most frequently at a median age of 18 months. Presentation in the neonatal period is rare, and there are very few reports of an antenatal diagnosis of hepatoblastoma. We recently encountered a neonate who presented with hemoperitoneum after rupture of a congenital hepatoblastoma during vaginal delivery. After successful right hepatectomy and adjuvant cis-platinum-based chemotherapy, the child is doing well. We draw attention to rarity of this condition and difficulty in definitively establishing a diagnosis both in the antenatal and neonatal periods and discuss the management dilemmas in congenital presentations of hepatoblastoma.

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