Pathogenesis of Microvascular Complications

Ferdinando Giacco; Michael Brownlee

doi:10.1002/9781444324808.ch35

Pathogenesis of Microvascular Complications

Ferdinando Giacco, Michael Brownlee

Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

10 Scopus citations

Original language	English (US)
Title of host publication	Textbook of Diabetes
Subtitle of host publication	Fourth Edition
Publisher	Wiley-Blackwell
Pages	553-574
Number of pages	22
ISBN (Print)	9781405191814
DOIs	https://doi.org/10.1002/9781444324808.ch35
State	Published - Jul 9 2010

Keywords

A single process underlying different hyperglycemia-induced pathogenic mechanisms: mitochondrial superoxide production
Determinants of individual susceptibility to hyperglycemia-induced damage
Hyperglycemia-induced mitochondrial superoxide production activates the five damaging pathways by inhibiting GAPDH
Hyperglycemia-induced mitochondrial superoxide production inhibits GAPDH by activating poly(ADP-ribose) polymerase
Mechanisms of hyperglycemia-induced damage
Nicotinic acid adenine dinucleotide phosphate (NADPH)
Potential mechanism-based therapeutic agents for diabetic complications
Receptor-mediated biologic effects of AGEs
Role of hyperglycemia in microvascular complications
Vascular endothelial growth factor (VEGF)

ASJC Scopus subject areas

General Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1002/9781444324808.ch35

Cite this

@inbook{967d286ede1f48a9a04de244c2440ee6,

title = "Pathogenesis of Microvascular Complications",

keywords = "A single process underlying different hyperglycemia-induced pathogenic mechanisms: mitochondrial superoxide production, Determinants of individual susceptibility to hyperglycemia-induced damage, Hyperglycemia-induced mitochondrial superoxide production activates the five damaging pathways by inhibiting GAPDH, Hyperglycemia-induced mitochondrial superoxide production inhibits GAPDH by activating poly(ADP-ribose) polymerase, Mechanisms of hyperglycemia-induced damage, Nicotinic acid adenine dinucleotide phosphate (NADPH), Potential mechanism-based therapeutic agents for diabetic complications, Receptor-mediated biologic effects of AGEs, Role of hyperglycemia in microvascular complications, Vascular endothelial growth factor (VEGF)",

author = "Ferdinando Giacco and Michael Brownlee",

year = "2010",

month = jul,

day = "9",

doi = "10.1002/9781444324808.ch35",

language = "English (US)",

isbn = "9781405191814",

pages = "553--574",

booktitle = "Textbook of Diabetes",

publisher = "Wiley-Blackwell",

}

TY - CHAP

T1 - Pathogenesis of Microvascular Complications

AU - Giacco, Ferdinando

AU - Brownlee, Michael

PY - 2010/7/9

Y1 - 2010/7/9

KW - A single process underlying different hyperglycemia-induced pathogenic mechanisms: mitochondrial superoxide production

KW - Determinants of individual susceptibility to hyperglycemia-induced damage

KW - Hyperglycemia-induced mitochondrial superoxide production activates the five damaging pathways by inhibiting GAPDH

KW - Hyperglycemia-induced mitochondrial superoxide production inhibits GAPDH by activating poly(ADP-ribose) polymerase

KW - Mechanisms of hyperglycemia-induced damage

KW - Nicotinic acid adenine dinucleotide phosphate (NADPH)

KW - Potential mechanism-based therapeutic agents for diabetic complications

KW - Receptor-mediated biologic effects of AGEs

KW - Role of hyperglycemia in microvascular complications

KW - Vascular endothelial growth factor (VEGF)

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U2 - 10.1002/9781444324808.ch35

DO - 10.1002/9781444324808.ch35

M3 - Chapter

AN - SCOPUS:84885979481

SN - 9781405191814

SP - 553

EP - 574

BT - Textbook of Diabetes

PB - Wiley-Blackwell

ER -

Pathogenesis of Microvascular Complications

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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Cite this