Paramecium genome survey: A pilot project

Philippe Dessen, Marek Zagulski, Robert Gromadka, Helmut Plattner, Roland Kissmehl, Eric Meyer, Mireille Bétermier, Joachim E. Schultz, Jürgen U. Linder, Ronald E. Pearlman, Ching Kung, Jim Forney, Birgit H. Satir, Judith L. Van Houten, Anne Marie Keller, Marine Froissard, Linda Sperling, Jean Cohen

Research output: Contribution to journalShort survey

56 Scopus citations

Abstract

A consortium of laboratories undertook a pilot sequencing project to gain insight into the genome of Paramecium. Plasmid-end sequencing of DNA fragments from the somatic nucleus together with similarity searches identified 722 potential protein-coding genes. High gene density and uniform small intron size make random sequencing of somatic chromosomes a cost-effective strategy for gene discovery in this organism.

Original languageEnglish (US)
Pages (from-to)306-308
Number of pages3
JournalTrends in Genetics
Volume17
Issue number6
DOIs
StatePublished - Jun 1 2001

ASJC Scopus subject areas

  • Genetics

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    Dessen, P., Zagulski, M., Gromadka, R., Plattner, H., Kissmehl, R., Meyer, E., Bétermier, M., Schultz, J. E., Linder, J. U., Pearlman, R. E., Kung, C., Forney, J., Satir, B. H., Van Houten, J. L., Keller, A. M., Froissard, M., Sperling, L., & Cohen, J. (2001). Paramecium genome survey: A pilot project. Trends in Genetics, 17(6), 306-308. https://doi.org/10.1016/S0168-9525(01)02307-1