Pain is not associated with worse office-based buprenorphine treatment outcomes

Aaron D. Fox, Nancy L. Sohler, Joanna L. Starrels, Yuming Ning, Angela Giovanniello, Chinazo O. Cunningham

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


Physical pain is common among individuals seeking treatment for opioid dependence. Pain may negatively impact addiction treatment. The authors prospectively studied opioid-dependent individuals initiating office-based buprenorphine treatment, comparing buprenorphine treatment outcomes (treatment retention and opioid use) among participants with and without pain (baseline pain or persistent pain). Among 82 participants, 60% reported baseline pain and 38% reported persistent pain. Overall, treatment retention was 56% and opioid use decreased from 89% to 26% over 6 months. In multivariable analyses, the authors found no association between pain and buprenorphine treatment outcomes. Opioid-dependent individuals with and without pain can achieve similar success with buprenorphine treatment.

Original languageEnglish (US)
Article number638734
Pages (from-to)361-365
Number of pages5
JournalSubstance Abuse
Issue number4
StatePublished - Oct 1 2012


  • Buprenorphine
  • chronic pain
  • opioid dependence

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Psychiatry and Mental health


Dive into the research topics of 'Pain is not associated with worse office-based buprenorphine treatment outcomes'. Together they form a unique fingerprint.

Cite this