Package architecture and component design for an implanted neural stimulator with closed loop control

Caroline K. Bjune, Thomas F. Marinis, Jeanne M. Brady, James Moran, Jesse Wheeler, Tirunelveli S. Sriram, Philip D. Parks, Alik S. Widge, Darin D. Dougherty, Emad N. Eskandar

Research output: Chapter in Book/Report/Conference proceedingConference contribution

7 Citations (Scopus)

Abstract

An implanted neural stimulator with closed loop control requires electrodes for stimulation pulses and recording neuron activity. Our system features arrays of 64 electrodes. Each electrode can be addressed through a cross bar switch, to enable it to be used for stimulation or recording. This electrode switch, a bank of low noise amplifiers with an integrated analog to digital converter, power conditioning electronics, and a communications and control gate array are co-located with the electrode array in a 14 millimeter diameter satellite package that is designed to be flush mounted in a skull burr hole. Our system features five satellite packages connected to a central hub processor-controller via ten conductor cables that terminate in a custom designed, miniaturized connector. The connector incorporates features of high reliability, military grade devices and utilizes three distinct seals to isolate the contacts from fluid permeation. The hub system is comprised of a connector header, hermetic electronics package, and rechargeable battery pack, which are mounted on and electrically interconnected by a flexible circuit board. The assembly is over molded with a compliant silicone rubber. The electronics package contains two antennas, a large coil, used for recharging the battery and a high bandwidth antenna that is used to download data and update software. The package is assembled from two machined alumina pieces, a flat base with brazed in, electrical feed through pins and a rectangular cover with rounded corners. Titanium seal rings are brazed onto these two pieces so that they can be sealed by laser welding. A third system antenna is incorporated in the flexible circuit board. It is used to communicate with an externally worn control package, which monitors the health of the system and allows both the user and clinician to control or modify various system function parameters.

Original languageEnglish (US)
Title of host publication2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages7825-7830
Number of pages6
Volume2015-November
ISBN (Electronic)9781424492718
DOIs
StatePublished - Nov 4 2015
Externally publishedYes
Event37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 - Milan, Italy
Duration: Aug 25 2015Aug 29 2015

Other

Other37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
CountryItaly
CityMilan
Period8/25/158/29/15

Fingerprint

Electrodes
Electronic equipment
Antennas
Seals
Switches
Satellites
Welding
Silicone Elastomers
Secondary batteries
Networks (circuits)
Aluminum Oxide
Low noise amplifiers
Laser beam welding
Digital to analog conversion
Titanium
Skull
Permeation
Silicones
Contacts (fluid mechanics)
Neurons

Keywords

  • Neural interfaces - Implantable systems
  • Neural interfaces - Microsystems and microfabrication
  • Neural stimulation - Deep brain

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

Cite this

Bjune, C. K., Marinis, T. F., Brady, J. M., Moran, J., Wheeler, J., Sriram, T. S., ... Eskandar, E. N. (2015). Package architecture and component design for an implanted neural stimulator with closed loop control. In 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 (Vol. 2015-November, pp. 7825-7830). [7320206] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2015.7320206

Package architecture and component design for an implanted neural stimulator with closed loop control. / Bjune, Caroline K.; Marinis, Thomas F.; Brady, Jeanne M.; Moran, James; Wheeler, Jesse; Sriram, Tirunelveli S.; Parks, Philip D.; Widge, Alik S.; Dougherty, Darin D.; Eskandar, Emad N.

2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015. Vol. 2015-November Institute of Electrical and Electronics Engineers Inc., 2015. p. 7825-7830 7320206.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Bjune, CK, Marinis, TF, Brady, JM, Moran, J, Wheeler, J, Sriram, TS, Parks, PD, Widge, AS, Dougherty, DD & Eskandar, EN 2015, Package architecture and component design for an implanted neural stimulator with closed loop control. in 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015. vol. 2015-November, 7320206, Institute of Electrical and Electronics Engineers Inc., pp. 7825-7830, 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015, Milan, Italy, 8/25/15. https://doi.org/10.1109/EMBC.2015.7320206
Bjune CK, Marinis TF, Brady JM, Moran J, Wheeler J, Sriram TS et al. Package architecture and component design for an implanted neural stimulator with closed loop control. In 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015. Vol. 2015-November. Institute of Electrical and Electronics Engineers Inc. 2015. p. 7825-7830. 7320206 https://doi.org/10.1109/EMBC.2015.7320206
Bjune, Caroline K. ; Marinis, Thomas F. ; Brady, Jeanne M. ; Moran, James ; Wheeler, Jesse ; Sriram, Tirunelveli S. ; Parks, Philip D. ; Widge, Alik S. ; Dougherty, Darin D. ; Eskandar, Emad N. / Package architecture and component design for an implanted neural stimulator with closed loop control. 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015. Vol. 2015-November Institute of Electrical and Electronics Engineers Inc., 2015. pp. 7825-7830
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