Over 15 years: the advancement of transcatheter aortic valve replacement

Thomas J. Cahill, Juan A. Terre, Isaac George

Research output: Contribution to journalArticlepeer-review

Abstract

The management of aortic stenosis has been revolutionized by transcatheter aortic valve replacement (TAVR). Initially only undertaken in patients at prohibitive or high surgical risk, as the evidence base and indications have expanded, TAVR is now approved and undertaken in patients at all risk levels. Evolution of valve technology, delivery systems and pathways for patient work-up have been rapid, with associated reductions in the complication profile, particularly vascular complications. Challenges remain as TAVR continues to advance, however, specifically achieving further reduction in paravalvular regurgitation, the requirement for permanent pacemaker implantation, and balancing the risks of thrombosis and bleeding. In this review, we outline the historical advances leading to contemporary TAVR practice, and discuss the future trajectory.

Original languageEnglish (US)
Pages (from-to)442-451
Number of pages10
JournalAnnals of Cardiothoracic Surgery
Volume9
Issue number6
DOIs
StatePublished - 2020

Keywords

  • Transcatheter aortic valve replacement (TAVR)
  • aortic stenosis
  • surgical aortic valve replacement (SAVR)
  • valvular heart disease

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine

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