One Patent Intracranial Collateral Predicts Tolerance of Flow Reversal during Carotid Angioplasty and Stenting

Iraklis I. Pipinos, George T. Pisimisis, Sathyaprasad Burjonrappa, Jason M. Johanning, G. Matthew Longo, Thomas G. Lynch

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Internal carotid artery (ICA) flow reversal is an effective means of cerebral protection during carotid stenting. Its main limitation is that in the absence of adequate collateral flow it may not be tolerated by the patient. The purpose of this study was to determine if preoperative identification of intracranial collaterals with computerized tomographic (CTA) or magnetic resonance (MRA) angiography can predict adequate collateral flow and neurological tolerance of ICA flow reversal for embolic protection. This was a study of patients undergoing transcervical carotid angioplasty and stenting. Neuroprotection was established by ICA flow reversal. All patients underwent preoperative cervical and cerebral noninvasive angiography with CTA or MRA and had at least one patent intracranial collateral. Mean carotid artery back pressure was measured. Neurological changes during carotid clamping and flow reversal were continuously monitored with electroencephalography (EEG). Thirty-seven patients with at least one patent intracranial collateral on brain imaging with CTA or MRA were included. Mean carotid artery back pressure was 58 mm Hg. All procedures were technically successful. No EEG changes were present with common carotid artery occlusion and ICA flow reversal. One patent intracranial collateral provides sufficient cerebral perfusion to perform carotid occlusion and flow reversal with absence of EEG changes. Continued progress in noninvasive imaging modalities is becoming increasingly helpful in our understanding of cerebral physiology and selection of patients for invasive carotid procedures.

Original languageEnglish (US)
Pages (from-to)32-38
Number of pages7
JournalAnnals of Vascular Surgery
Volume23
Issue number1
DOIs
StatePublished - Jan 2009
Externally publishedYes

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Internal Carotid Artery
Angioplasty
Electroencephalography
Carotid Arteries
Magnetic Resonance Spectroscopy
Pressure
Cerebral Angiography
Magnetic Resonance Angiography
Common Carotid Artery
Constriction
Neuroimaging
Patient Selection
Perfusion

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

One Patent Intracranial Collateral Predicts Tolerance of Flow Reversal during Carotid Angioplasty and Stenting. / Pipinos, Iraklis I.; Pisimisis, George T.; Burjonrappa, Sathyaprasad; Johanning, Jason M.; Longo, G. Matthew; Lynch, Thomas G.

In: Annals of Vascular Surgery, Vol. 23, No. 1, 01.2009, p. 32-38.

Research output: Contribution to journalArticle

Pipinos, Iraklis I. ; Pisimisis, George T. ; Burjonrappa, Sathyaprasad ; Johanning, Jason M. ; Longo, G. Matthew ; Lynch, Thomas G. / One Patent Intracranial Collateral Predicts Tolerance of Flow Reversal during Carotid Angioplasty and Stenting. In: Annals of Vascular Surgery. 2009 ; Vol. 23, No. 1. pp. 32-38.
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