Obesity, bariatric surgery, and iron deficiency

True, true, true and related

Aileen L. Love, Henny H. Billett

Research output: Contribution to journalArticle

104 Citations (Scopus)

Abstract

Morbid obesity is a health problem that has been shown to be refractory to diet, exercise, and medical treatment. Surgeries designed to promote weight loss, termed bariatric surgery and typically involving a gastric bypass procedure, have recently been implemented to treat obesity with high success rates. However, long-term sequelae can result in micronutrient deficiencies. This review will focus on iron deficiency and its association with obesity and bariatric surgery. Iron deficiency develops after gastric bypass for several reasons including intolerance for red meat, diminished gastric acid secretion, and exclusion of the duodenum from the alimentary tract. Menstruating women, pregnant women, and adolescents may be particularly predisposed toward developing iron deficiency and microcytic anemias after bypass surgery. Preoperative assessment of patients should include a complete hematological work-up, including measurement of iron stores. Postoperatively, oral iron prophylaxis and vitamin C in addition to a multivitamin should be prescribed for bypass patients, especially for vulnerable populations. Once iron deficiency has developed, it may prove refractory to oral treatment, and require parenteral iron, blood transfusions, or surgical interventions. Bariatric surgery patients require lifelong follow-up of hematological and iron parameters since iron deficiency and anemia may develop years after surgery.

Original languageEnglish (US)
Pages (from-to)403-409
Number of pages7
JournalAmerican Journal of Hematology
Volume83
Issue number5
DOIs
StatePublished - May 2008

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Bariatric Surgery
Iron
Obesity
Gastric Bypass
Iron-Deficiency Anemias
Morbid Obesity
Micronutrients
Gastric Acid
Vulnerable Populations
Duodenum
Blood Transfusion
Ascorbic Acid
Weight Loss
Pregnant Women
Exercise
Diet
Health
Therapeutics

ASJC Scopus subject areas

  • Hematology

Cite this

Obesity, bariatric surgery, and iron deficiency : True, true, true and related. / Love, Aileen L.; Billett, Henny H.

In: American Journal of Hematology, Vol. 83, No. 5, 05.2008, p. 403-409.

Research output: Contribution to journalArticle

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