Nutritional management of insulin resistance in nonalcoholic fatty liver disease (NAFLD)

Beth A. Conlon, Jeannette M. Beasley, Karin Aebersold, Sunil S. Jhangiani, Judith Wylie-Rosett

Research output: Contribution to journalReview article

45 Scopus citations

Abstract

Nonalcoholic fatty liver disease (NAFLD) is an emerging global health concern. It is the most common form of chronic liver disease in Western countries, affecting both adults and children. NAFLD encompasses a broad spectrum of fatty liver disease, ranging from simple steatosis (NAFL) to nonalcoholic steatohepatitis (NASH), and is strongly associated with obesity, insulin resistance, and dyslipidemia. First-line therapy for NAFLD includes weight loss achieved through diet and physical activity. However, there is a lack of evidenced-based dietary recommendations. The American Diabetes Association's (ADA) recommendations that aim to reduce the risk of diabetes and cardiovascular disease may also be applicable to the NAFLD population. The objectives of this review are to: (1) provide an overview of NAFLD in the context of insulin resistance, and (2) provide a rationale for applying relevant aspects of the ADA recommendations to the nutritional management of NAFLD.

Original languageEnglish (US)
Pages (from-to)4093-4114
Number of pages22
JournalNutrients
Volume5
Issue number10
DOIs
StatePublished - Oct 11 2013

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Keywords

  • Diabetes
  • Hepatic steatosis
  • Insulin resistance
  • Macronutrients
  • Nonalcoholic fatty liver disease
  • Nonalcoholic steatohepatitis
  • Nutrition
  • Review

ASJC Scopus subject areas

  • Food Science
  • Nutrition and Dietetics

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