TY - JOUR
T1 - Nonosseous, Nonurologic Uptake on Bone Scintigraphy
T2 - Atlas and Analysis
AU - Zuckier, Lionel S.
AU - Freeman, Leonard M.
PY - 2010/7
Y1 - 2010/7
N2 - Uptake in nonosseous, nonurologic tissues is occasionally found in the performance of bone scintigraphy. Proper interpretation of these cases depends on identifying the involved organs and appreciating the significance of the uptake. Because of the rarity of these findings and a relative de-emphasis of planar imaging in radiologic imaging, current era trainees may exhibit difficulty in identifying organs on planar projections. The first section of this work consists of an image atlas depicting uptake by various nonosseous, nonurologic organs on planar scintigraphy. In the second section, we discuss the etiologies of soft-tissue uptake, organized according to mechanisms of accretion: (1) metastatic calcification, (2) dystrophic calcification, (3) metabolic uptake, and (4) compartmental sequestration. Spurious or artifactual uptake represents a fifth category of apparent soft-tissue uptake which will also be reviewed. Causes of organ uptake span the gamut of trivial and artifactual to those reflecting serious malignant and systemic disorders. Clues as to etiology may be gleaned from grouping of abnormalities.
AB - Uptake in nonosseous, nonurologic tissues is occasionally found in the performance of bone scintigraphy. Proper interpretation of these cases depends on identifying the involved organs and appreciating the significance of the uptake. Because of the rarity of these findings and a relative de-emphasis of planar imaging in radiologic imaging, current era trainees may exhibit difficulty in identifying organs on planar projections. The first section of this work consists of an image atlas depicting uptake by various nonosseous, nonurologic organs on planar scintigraphy. In the second section, we discuss the etiologies of soft-tissue uptake, organized according to mechanisms of accretion: (1) metastatic calcification, (2) dystrophic calcification, (3) metabolic uptake, and (4) compartmental sequestration. Spurious or artifactual uptake represents a fifth category of apparent soft-tissue uptake which will also be reviewed. Causes of organ uptake span the gamut of trivial and artifactual to those reflecting serious malignant and systemic disorders. Clues as to etiology may be gleaned from grouping of abnormalities.
UR - http://www.scopus.com/inward/record.url?scp=77952692611&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77952692611&partnerID=8YFLogxK
U2 - 10.1053/j.semnuclmed.2010.02.003
DO - 10.1053/j.semnuclmed.2010.02.003
M3 - Review article
C2 - 20513447
AN - SCOPUS:77952692611
SN - 0001-2998
VL - 40
SP - 242
EP - 256
JO - Seminars in nuclear medicine
JF - Seminars in nuclear medicine
IS - 4
ER -