New routes to old places: PIK3R1 and PIK3R2 join PIK3CA and PTEN as endometrial cancer genes

Sandra Herrero-Gonzalez, Antonio Di Cristofano

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Cheung and colleagues identify PIK3R1 and PIK3R2, the genes encoding the α and β isoforms of the phosphatidylinositol 3-kinase (PI3K) p85 regulatory subunit, as additional mutation targets in endometrial cancer, and describe a novel mechanism leading to PTEN loss.

Original languageEnglish (US)
Pages (from-to)106-107
Number of pages2
JournalCancer discovery
Volume1
Issue number2
DOIs
StatePublished - Jul 18 2011

ASJC Scopus subject areas

  • Oncology

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