Neuro-Behçet disease presenting with acute psychosis in an adolescent

Puja Patel, Mitchell Steinschneider, Alexis Boneparth, George Lantos

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Behçet disease is a systemic vasculitis of unknown etiology that can affect the neurologic system. Neuro-Behçet disease is not well defined in children and adolescents, and the diagnosis is difficult to make in this population as they often present with insufficient symptoms to meet diagnostic criteria. Psychiatric symptoms as the initial manifestation of neuro-Behçet disease has rarely been reported. We describe a 17-year-old boy who presented with acute psychosis and was subsequently diagnosed with neuro-Behçet disease. A rare combination of both cerebral venous thrombosis and parenchymal central nervous system involvement was identified by neuroimaging. Although treatment guidelines for neuro-Behçet disease are limited, the patient made demonstrative clinical and radiographic improvement with a combination of corticosteroids, anticoagulation, and immunosuppressants, including a tumor necrosis factor-α (TNFα) blocking agent.

Original languageEnglish (US)
Pages (from-to)NP86-NP91
JournalJournal of Child Neurology
Volume29
Issue number9
DOIs
StatePublished - 2014

Fingerprint

Psychotic Disorders
Intracranial Thrombosis
Systemic Vasculitis
Immunosuppressive Agents
Neuroimaging
Venous Thrombosis
Nervous System
Psychiatry
Adrenal Cortex Hormones
Central Nervous System
Tumor Necrosis Factor-alpha
Guidelines
Population
Therapeutics

Keywords

  • Acute psychosis
  • Anti-tumor necrosis factor-α
  • Cerebral venous thrombosis
  • Childhood
  • Neuro-Behçet disease

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Medicine(all)

Cite this

Neuro-Behçet disease presenting with acute psychosis in an adolescent. / Patel, Puja; Steinschneider, Mitchell; Boneparth, Alexis; Lantos, George.

In: Journal of Child Neurology, Vol. 29, No. 9, 2014, p. NP86-NP91.

Research output: Contribution to journalArticle

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