Neural correlates of auditory perceptual awareness and release from informational masking recorded directly from human cortex: A case study

Andrew R. Dykstra, Eric Halgren, Alexander Gutschalk, Emad N. Eskandar, Sydney S. Cash

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

In complex acoustic environments, even salient supra-threshold sounds sometimes go unperceived, a phenomenon known as informational masking. The neural basis of informational masking (and its release) has not been well-characterized, particularly outside auditory cortex. We combined electrocorticography in a neurosurgical patient undergoing invasive epilepsy monitoring with trial-by-trial perceptual reports of isochronous target-tone streams embedded in random multi-tone maskers. Awareness of such masker-embedded target streams was associated with a focal negativity between 100 and 200 ms and high-gamma activity (HGA) between 50 and 250 ms (both in auditory cortex on the posterolateral superior temporal gyrus) as well as a broad P3b-like potential (between ~300 and 600 ms) with generators in ventrolateral frontal and lateral temporal cortex. Unperceived target tones elicited drastically reduced versions of such responses, if at all. While it remains unclear whether these responses reflect conscious perception, itself, as opposed to pre- or post-perceptual processing, the results suggest that conscious perception of target sounds in complex listening environments may engage diverse neural mechanisms in distributed brain areas.

Original languageEnglish (US)
Article number472
JournalFrontiers in Neuroscience
Volume10
Issue numberOCT
DOIs
StatePublished - Oct 20 2016
Externally publishedYes

Fingerprint

Auditory Cortex
Temporal Lobe
Acoustics
Epilepsy
Brain
Electrocorticography

Keywords

  • Auditory cortex
  • Conscious perception
  • Electrocorticography
  • High-gamma activity
  • Informational masking

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Neural correlates of auditory perceptual awareness and release from informational masking recorded directly from human cortex : A case study. / Dykstra, Andrew R.; Halgren, Eric; Gutschalk, Alexander; Eskandar, Emad N.; Cash, Sydney S.

In: Frontiers in Neuroscience, Vol. 10, No. OCT, 472, 20.10.2016.

Research output: Contribution to journalArticle

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