@article{fe64eaf209d14b0a93031421147c366e,
title = "Neonatal hypotonia",
abstract = "Neonatal hypotonia represents a commonly encountered issue in the NICU and newborn nursery. Low tone is not a diagnosis in itself but, rather, a symptom. This review focuses on the special case of diffuse hypotonia presenting in the neonatal period. Etiologies are broad and include systemic illness, dysfunction of the central nervous system, or dysfunction of the peripheral nervous system and motor unit (ranging from disorders of the anterior horn cell to primary muscle disease). In this time of rapidly expanding therapeutic options for many diagnoses causing hypotonia, expeditious evaluation is crucial. Careful physical examination, thorough history, and appropriately selected ancillary testing guides the diagnostic process.",
author = "Elissa Yozawitz and Leslie Delfiner and Mosh{\'e}, {Solomon L.}",
note = "Funding Information: AUTHOR DISCLOSURE Drs Yozawitz and Delfiner have disclosed no financial relationships relevant to this article. Dr Mosh{\'e} is the Charles Frost Chair in Neurosurgery and Neurology and is partially funded by grants from the NIH (U54 NS100064 and NS43209), US Department of Defense (W81XWH-13-1-0180), CURE Infantile Spasms Initiative, the Heffer Family and the Segal Family foundations, and the Abbe Goldstein/Joshua Lurie and Laurie Marsh/Dan Levitz families. He is serving as associate editor of Neurobiology of Disease and is on the editorial board of Brain and Development, Pediatric Neurology, and Physiological Research. He receives annual compensation from Elsevier for his work as associate editor for Neurobiology of Disease and royalties from 2 books he has coedited. He receives consultant fees from Eisai, Mallinckrodt, and UCB. This commentary does not contain a discussion of an unapproved/ investigative use of a commercial product/ device. Publisher Copyright: {\textcopyright} 2018, American Academy of Pediatrics. All rights reserved. Copyright: Copyright 2018 Elsevier B.V., All rights reserved.",
year = "2018",
month = aug,
doi = "10.1542/neo.19-8-e445",
language = "English (US)",
volume = "19",
pages = "e445--e455",
journal = "Pediatrics in Review",
issn = "0191-9601",
publisher = "American Academy of Pediatrics",
number = "8",
}