Cultured mouse myeloma cells frequently generate variants in immunoglobulin expression and structure. In this paper the authors will review the phenotypes of the variants which have been identified and discuss the mechanisms which may be responsible for the somatic instability of the immunoglobulin genes in mouse myeloma cells.
|Original language||English (US)|
|Number of pages||22|
|Journal||Critical reviews in immunology|
|Publication status||Published - Sep 1 1981|
ASJC Scopus subject areas
- Immunology and Allergy