Mural vegetations at the site of endocardial trauma in infective endocarditis complicating idiopathic hypertrophic subaortic stenosis

Thierry H. LeJemtel, Stephen M. Factor, Mordecai Koenigsberg, Michael O'Reilly, Robert Frater, Edmund H. Sonnenblick

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16 Scopus citations


In two patients infective endocarditis developed as the primary manifestation of idiopathic hypertrophic subaortic stenosis. Infected vegetations were present on the mitral and aortic valves. In addition, bacterial vegetations were observed on the septal endocardium at the site of contact between the mitral valve leaflet and the hypertrophic septum. Thus, chronic endocardial trauma, a common finding in idiopathic hypertrophic subaortic stenosis, may provide a fertile nidus for the development of bacterial vegetation.

Original languageEnglish (US)
Pages (from-to)569-574
Number of pages6
JournalThe American Journal of Cardiology
Issue number3
Publication statusPublished - Sep 1979


ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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