Models for the initiation and growth of extracellular lipid liposomes in arterial intima and valves

Yongyi Yin, Kwang Hee Lim, Sheldon Weinbaum, Shu Chien, David Rumschitzki

Research output: Contribution to conferencePaper

Abstract

A hierarchy of simple nucleation-polymerization models is proposed to describe liposome formation and growth. The cholesterol-fed rabbit intima data seem to result from the short-term nonuniform intimal history of low-density lipoprotein (LDL) supply, which is a consequence of the focal nature of the transarterial-endothelial LDL flow through isolated transient leaky junctions. An appropriate valve water/LDL transport model is combined with the nucleation/polymerization models to explain the data.

Original languageEnglish (US)
Number of pages1
StatePublished - Jan 1 1997
EventProceedings of the 1997 Bioengineering Conference - Sunriver, OR, USA
Duration: Jun 11 1997Jun 15 1997

Other

OtherProceedings of the 1997 Bioengineering Conference
CitySunriver, OR, USA
Period6/11/976/15/97

ASJC Scopus subject areas

  • Engineering(all)

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    Yin, Y., Lim, K. H., Weinbaum, S., Chien, S., & Rumschitzki, D. (1997). Models for the initiation and growth of extracellular lipid liposomes in arterial intima and valves. Paper presented at Proceedings of the 1997 Bioengineering Conference, Sunriver, OR, USA, .