Mitochondrial-type hsp70 genes of the amitochondriate protists, Giardia intestinalis, Entamoeba histolytica and two microsporidians

Nobuko Arisue, Lidya B. Sánchez, Louis M. Weiss, Miklós Müller, Tetsuo Hashimoto

Research output: Contribution to journalArticle

57 Scopus citations

Abstract

Genes encoding putative mitochondrial-type heat shock protein 70 (mit-hsp70) were isolated and sequenced from amitochondriate protists, Giardia intestinalis, Entamoeba histolytica, and two microsporidians, Encephalitozoon hellem and Glugea plecoglossi. The deduced mit-hsp70 sequences were analyzed by sequence alignments and phylogenetic reconstructions. The mit-hsp70 sequence of these four amitochondriate protists were divergent from other mit-hsp70 sequences of mitochondriate eukaryotes. However, all of these sequences were clearly located within a eukaryotic mitochondrial clade in the tree including various type hsp70 sequences, supporting the emerging notion that none of these amitochondriate lineages are primitively amitochodrial, but lost their mitochondria secondarily in their evolutionary past.

Original languageEnglish (US)
Pages (from-to)9-16
Number of pages8
JournalParasitology International
Volume51
Issue number1
DOIs
StatePublished - Mar 19 2002

Keywords

  • Amitochondriate protists
  • Entamoeba
  • Giardia
  • Hsp70
  • Microsporidia
  • Phylogeny

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

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