Microtubule dynamics: Patronin, protector of the minus end

Brian P. O'Rourke; David J. Sharp

doi:10.1016/j.cub.2010.12.011

Microtubule dynamics: Patronin, protector of the minus end

Brian P. O'Rourke, David J. Sharp

Molecular Pharmacology

Research output: Contribution to journal › Short survey › peer-review

5 Scopus citations

Abstract

It has long been surmised that cellular microtubules are capped at the minus ends to prevent their depolymerization. A recent study provides the first definitive identification of a minus-end-specific capping protein, termed Patronin, which protects the microtubule arrays of both mitotic and interphase cells.

Original language	English (US)
Pages (from-to)	R77-R79
Journal	Current Biology
Volume	21
Issue number	2
DOIs	https://doi.org/10.1016/j.cub.2010.12.011
State	Published - Jan 25 2011

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology
General Agricultural and Biological Sciences

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title = "Microtubule dynamics: Patronin, protector of the minus end",

abstract = "It has long been surmised that cellular microtubules are capped at the minus ends to prevent their depolymerization. A recent study provides the first definitive identification of a minus-end-specific capping protein, termed Patronin, which protects the microtubule arrays of both mitotic and interphase cells.",

author = "O'Rourke, {Brian P.} and Sharp, {David J.}",

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AU - Sharp, David J.

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N2 - It has long been surmised that cellular microtubules are capped at the minus ends to prevent their depolymerization. A recent study provides the first definitive identification of a minus-end-specific capping protein, termed Patronin, which protects the microtubule arrays of both mitotic and interphase cells.

AB - It has long been surmised that cellular microtubules are capped at the minus ends to prevent their depolymerization. A recent study provides the first definitive identification of a minus-end-specific capping protein, termed Patronin, which protects the microtubule arrays of both mitotic and interphase cells.

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DO - 10.1016/j.cub.2010.12.011

M3 - Short survey

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SN - 0960-9822

VL - 21

SP - R77-R79

JO - Current Biology

JF - Current Biology

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ER -

Microtubule dynamics: Patronin, protector of the minus end

Abstract

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