Microtubule dynamics: Patronin, protector of the minus end

Brian P. O'Rourke, David J. Sharp

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

It has long been surmised that cellular microtubules are capped at the minus ends to prevent their depolymerization. A recent study provides the first definitive identification of a minus-end-specific capping protein, termed Patronin, which protects the microtubule arrays of both mitotic and interphase cells.

Original languageEnglish (US)
JournalCurrent Biology
Volume21
Issue number2
DOIs
StatePublished - Jan 25 2011

Fingerprint

Depolymerization
Microtubules
microtubules
depolymerization
Interphase
interphase
Proteins
proteins
cells

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Microtubule dynamics : Patronin, protector of the minus end. / O'Rourke, Brian P.; Sharp, David J.

In: Current Biology, Vol. 21, No. 2, 25.01.2011.

Research output: Contribution to journalArticle

@article{602132ea49364de2af12ff0baea3cc48,
title = "Microtubule dynamics: Patronin, protector of the minus end",
abstract = "It has long been surmised that cellular microtubules are capped at the minus ends to prevent their depolymerization. A recent study provides the first definitive identification of a minus-end-specific capping protein, termed Patronin, which protects the microtubule arrays of both mitotic and interphase cells.",
author = "O'Rourke, {Brian P.} and Sharp, {David J.}",
year = "2011",
month = "1",
day = "25",
doi = "10.1016/j.cub.2010.12.011",
language = "English (US)",
volume = "21",
journal = "Current Biology",
issn = "0960-9822",
publisher = "Cell Press",
number = "2",

}

TY - JOUR

T1 - Microtubule dynamics

T2 - Patronin, protector of the minus end

AU - O'Rourke, Brian P.

AU - Sharp, David J.

PY - 2011/1/25

Y1 - 2011/1/25

N2 - It has long been surmised that cellular microtubules are capped at the minus ends to prevent their depolymerization. A recent study provides the first definitive identification of a minus-end-specific capping protein, termed Patronin, which protects the microtubule arrays of both mitotic and interphase cells.

AB - It has long been surmised that cellular microtubules are capped at the minus ends to prevent their depolymerization. A recent study provides the first definitive identification of a minus-end-specific capping protein, termed Patronin, which protects the microtubule arrays of both mitotic and interphase cells.

UR - http://www.scopus.com/inward/record.url?scp=79251531115&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79251531115&partnerID=8YFLogxK

U2 - 10.1016/j.cub.2010.12.011

DO - 10.1016/j.cub.2010.12.011

M3 - Article

C2 - 21256440

AN - SCOPUS:79251531115

VL - 21

JO - Current Biology

JF - Current Biology

SN - 0960-9822

IS - 2

ER -