Meningeal Rosai-Dorfman disease: report of three cases and literature review.

R. Kitai; J. Llena; A. Hirano; K. Ido; K. Sato; T. Kubota

doi:10.1007/BF02478925

Meningeal Rosai-Dorfman disease: report of three cases and literature review.

R. Kitai, J. Llena, A. Hirano, K. Ido, K. Sato, T. Kubota

Pathology

Research output: Contribution to journal › Review article › peer-review

35 Scopus citations

Abstract

Rosai-Dorfman disease is a well-recognized clinicopathological entity, which in rare cases affects the central nervous system, where it mimics meningioma. We describe three cases and review the literature. Histological and immunohistochemical confirmation is essential for definitive diagnosis. In addition to emperipolesis (lymphophagocytosis), reactivity for S-100 and CD68 and nonreactivity for CD-la immunostaining are characteristic features of this histioproliferative disease. In contrast to meningioma, this tumor usually occurs in young males and infiltrates the brain parenchyma.

Original language	English (US)
Pages (from-to)	49-54
Number of pages	6
Journal	Brain tumor pathology
Volume	18
Issue number	1
DOIs	https://doi.org/10.1007/BF02478925
State	Published - 2001

ASJC Scopus subject areas

Oncology
Clinical Neurology
Cancer Research

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10.1007/BF02478925

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title = "Meningeal Rosai-Dorfman disease: report of three cases and literature review.",

abstract = "Rosai-Dorfman disease is a well-recognized clinicopathological entity, which in rare cases affects the central nervous system, where it mimics meningioma. We describe three cases and review the literature. Histological and immunohistochemical confirmation is essential for definitive diagnosis. In addition to emperipolesis (lymphophagocytosis), reactivity for S-100 and CD68 and nonreactivity for CD-la immunostaining are characteristic features of this histioproliferative disease. In contrast to meningioma, this tumor usually occurs in young males and infiltrates the brain parenchyma.",

author = "R. Kitai and J. Llena and A. Hirano and K. Ido and K. Sato and T. Kubota",

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doi = "10.1007/BF02478925",

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T1 - Meningeal Rosai-Dorfman disease

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AU - Kitai, R.

AU - Llena, J.

AU - Hirano, A.

AU - Ido, K.

AU - Sato, K.

AU - Kubota, T.

PY - 2001

Y1 - 2001

N2 - Rosai-Dorfman disease is a well-recognized clinicopathological entity, which in rare cases affects the central nervous system, where it mimics meningioma. We describe three cases and review the literature. Histological and immunohistochemical confirmation is essential for definitive diagnosis. In addition to emperipolesis (lymphophagocytosis), reactivity for S-100 and CD68 and nonreactivity for CD-la immunostaining are characteristic features of this histioproliferative disease. In contrast to meningioma, this tumor usually occurs in young males and infiltrates the brain parenchyma.

AB - Rosai-Dorfman disease is a well-recognized clinicopathological entity, which in rare cases affects the central nervous system, where it mimics meningioma. We describe three cases and review the literature. Histological and immunohistochemical confirmation is essential for definitive diagnosis. In addition to emperipolesis (lymphophagocytosis), reactivity for S-100 and CD68 and nonreactivity for CD-la immunostaining are characteristic features of this histioproliferative disease. In contrast to meningioma, this tumor usually occurs in young males and infiltrates the brain parenchyma.

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Meningeal Rosai-Dorfman disease: report of three cases and literature review.

Abstract

ASJC Scopus subject areas

UN SDGs

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