TY - JOUR
T1 - Mastocytosis, melanoma and sarcoidosis
AU - Lee-Wong, Mary
AU - Laufer, Michael
AU - Karagic, Merhunisa
N1 - Copyright:
Copyright 2011 Elsevier B.V., All rights reserved.
PY - 2009
Y1 - 2009
N2 - This report describes a 30-year-old man with a history of malignant melanoma who developed various signs, symptoms and laboratory findings which were consistent with systemic mastocytosis. The patient also developed night sweats, weight loss and dyspnea, along with bilateral hilar lymphadenopathy and diffuse pulmonary infiltrates. A transbronchial biopsy revealed non-necrotizing granulomas that were diagnosed as sarcoidosis. We believe this is the first report of melanoma and mastocytosis in the same patient, suggesting a possible genetic link between the two diseases. The pulmonary manifestations were ultimately found to be due to sarcoidosis.
AB - This report describes a 30-year-old man with a history of malignant melanoma who developed various signs, symptoms and laboratory findings which were consistent with systemic mastocytosis. The patient also developed night sweats, weight loss and dyspnea, along with bilateral hilar lymphadenopathy and diffuse pulmonary infiltrates. A transbronchial biopsy revealed non-necrotizing granulomas that were diagnosed as sarcoidosis. We believe this is the first report of melanoma and mastocytosis in the same patient, suggesting a possible genetic link between the two diseases. The pulmonary manifestations were ultimately found to be due to sarcoidosis.
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M3 - Article
AN - SCOPUS:79960941593
SN - 1532-0642
VL - 7
JO - Internet Journal of Asthma, Allergy and Immunology
JF - Internet Journal of Asthma, Allergy and Immunology
IS - 1
ER -