This report describes a 30-year-old man with a history of malignant melanoma who developed various signs, symptoms and laboratory findings which were consistent with systemic mastocytosis. The patient also developed night sweats, weight loss and dyspnea, along with bilateral hilar lymphadenopathy and diffuse pulmonary infiltrates. A transbronchial biopsy revealed non-necrotizing granulomas that were diagnosed as sarcoidosis. We believe this is the first report of melanoma and mastocytosis in the same patient, suggesting a possible genetic link between the two diseases. The pulmonary manifestations were ultimately found to be due to sarcoidosis.
|Original language||English (US)|
|Journal||Internet Journal of Asthma, Allergy and Immunology|
|State||Published - 2009|
ASJC Scopus subject areas
- Immunology and Allergy
- Pulmonary and Respiratory Medicine