The review addresses issues pertinent to Mn accumulation and its mechanisms of transport, its neurotoxicity and mechanisms of neurodegeneration. The role of mitochondria and glia in this process is emphasized. We also discuss gene x environment interactions, focusing on the interplay between genes linked to Parkinson's disease (PD) and sensitivity to Mn.
|Original language||English (US)|
|Number of pages||33|
|Journal||Metal Ions in Life Sciences|
|State||Published - 2013|
- Divalent metal transporter 1 (DMT1)
ASJC Scopus subject areas