Loss and reappearance of Rh(o)(D) antigen on the red blood cells of an individual with acute myelogenous leukemia

K. Mohandas, V. Najfield, H. Gilbert, P. Azar, D. Skerrett

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Complete loss of Rh(o)(D) antigen from red blood cells (RBCs) of individuals with hematologic disorders, though not frequent, has been reported. This case reports the loss of D antigen on the RBCs of a patient with acute myelogenous leukemia and its reappearance when he was in remission. Loss of D antigen expression coincided with worsening clinical and cytogenetic disease. At the time of D antigen loss, the patient also had cytogenetic abnormalities in the bone marrow cells. When he was in remission, the chromosomal abnormalities were no longer detectable, and his RBCs regained D antigen expression.

Original languageEnglish (US)
Pages (from-to)134-135
Number of pages2
JournalImmunohematology
Volume10
Issue number4
StatePublished - 1994
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Hematology

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