Loss and reappearance of Rh(o)(D) antigen on the red blood cells of an individual with acute myelogenous leukemia

Kala Mohandas, V. Najfield, H. Gilbert, P. Azar, D. Skerrett

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Complete loss of Rh(o)(D) antigen from red blood cells (RBCs) of individuals with hematologic disorders, though not frequent, has been reported. This case reports the loss of D antigen on the RBCs of a patient with acute myelogenous leukemia and its reappearance when he was in remission. Loss of D antigen expression coincided with worsening clinical and cytogenetic disease. At the time of D antigen loss, the patient also had cytogenetic abnormalities in the bone marrow cells. When he was in remission, the chromosomal abnormalities were no longer detectable, and his RBCs regained D antigen expression.

Original languageEnglish (US)
Pages (from-to)134-135
Number of pages2
JournalImmunohematology
Volume10
Issue number4
StatePublished - 1994
Externally publishedYes

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Acute Myeloid Leukemia
Erythrocytes
Antigens
Chromosome Aberrations
Cytogenetics
Bone Marrow Cells

ASJC Scopus subject areas

  • Immunology
  • Hematology

Cite this

Loss and reappearance of Rh(o)(D) antigen on the red blood cells of an individual with acute myelogenous leukemia. / Mohandas, Kala; Najfield, V.; Gilbert, H.; Azar, P.; Skerrett, D.

In: Immunohematology, Vol. 10, No. 4, 1994, p. 134-135.

Research output: Contribution to journalArticle

Mohandas, Kala ; Najfield, V. ; Gilbert, H. ; Azar, P. ; Skerrett, D. / Loss and reappearance of Rh(o)(D) antigen on the red blood cells of an individual with acute myelogenous leukemia. In: Immunohematology. 1994 ; Vol. 10, No. 4. pp. 134-135.
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