Lonidamine: A hyperthermic sensitizer of hela cells in culture and of the meth-a tumor in vivo

J. H. Kim, Sang Hie Kim, Alan Alfieri, Charles W. Young, Bruno Silvestrini

Research output: Contribution to journalArticle

40 Scopus citations

Abstract

Lonidamine was studied in HeLa cell cultures and BALB/c mice with Meth-A fibrosarcoma. Lonidamine is a hyperthermia sensitizer, both in vivo and in vivo. In vitro the potentiating effects were higher at low pH conditions.

Original languageEnglish (US)
Pages (from-to)30-35
Number of pages6
JournalOncology (Switzerland)
Volume41
DOIs
StatePublished - Jan 1 1984

Keywords

  • HeLa cells
  • Hyperthermia
  • Lonidamine
  • Murine Meth-A tumor

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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