Lonidamine

A hyperthermic sensitizer of hela cells in culture and of the meth-a tumor in vivo

J. H. Kim, Sang Hie Kim, Alan Alfieri, Charles W. Young, Bruno Silvestrini

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

Lonidamine was studied in HeLa cell cultures and BALB/c mice with Meth-A fibrosarcoma. Lonidamine is a hyperthermia sensitizer, both in vivo and in vivo. In vitro the potentiating effects were higher at low pH conditions.

Original languageEnglish (US)
Pages (from-to)30-35
Number of pages6
JournalONCOLOGY (United States)
Volume41
DOIs
StatePublished - 1984
Externally publishedYes

Fingerprint

HeLa Cells
Cell Culture Techniques
Fibrosarcoma
Neoplasms
Fever
lonidamine
In Vitro Techniques

Keywords

  • HeLa cells
  • Hyperthermia
  • Lonidamine
  • Murine Meth-A tumor

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Lonidamine : A hyperthermic sensitizer of hela cells in culture and of the meth-a tumor in vivo. / Kim, J. H.; Kim, Sang Hie; Alfieri, Alan; Young, Charles W.; Silvestrini, Bruno.

In: ONCOLOGY (United States), Vol. 41, 1984, p. 30-35.

Research output: Contribution to journalArticle

Kim, J. H. ; Kim, Sang Hie ; Alfieri, Alan ; Young, Charles W. ; Silvestrini, Bruno. / Lonidamine : A hyperthermic sensitizer of hela cells in culture and of the meth-a tumor in vivo. In: ONCOLOGY (United States). 1984 ; Vol. 41. pp. 30-35.
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