Liver-Directed Gene Therapy

Betsy T. Kren, Clifford J. Steer, Namita Roy Chowdhury, Jayanta Roy Chowdhury

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations
Original languageEnglish (US)
Title of host publicationThe Liver
Subtitle of host publicationBiology and Pathobiology: Fifth Edition
PublisherJohn Wiley & Sons, Ltd.
Number of pages26
ISBN (Print)9780470723135
StatePublished - Oct 6 2009


  • Apolipoprotein B mRNA editing enzyme (APOBEC-1)
  • Gene transfer to liver
  • Liver-directed gene therapy
  • Liver-directed gene therapy for diverse therapeutic strategies
  • New non-viral technologies, Sleeping Beauty transposons for gene augmentation
  • Non-viral vectors
  • Ornithine transcarbamylase (OTC)-deficient pups
  • Recombinant viruses
  • Retroviruses integrating complementary DNA into host genome
  • Single-stranded oligonucleotides (SSOs) and single base mismatch

ASJC Scopus subject areas

  • Medicine(all)

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