Letrozole significantly improves growth potential in a pubertal boy with growth hormone deficiency

Ping Zhou; Bina Shah; Kris Prasad; Raphael David

doi:10.1542/peds.2004-1536

Letrozole significantly improves growth potential in a pubertal boy with growth hormone deficiency

Ping Zhou, Bina Shah, Kris Prasad, Raphael David

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Clinical experience with using an aromatase inhibitor to suppress estrogen production during puberty for improvement of growth potential in adolescents with short stature is limited. This report documents treatment of such a patient with a combination of growth hormone and letrozole, a third-generation aromatase inhibitor. Our case demonstrates a favorable outcome on a short-term basis.

Original language	English (US)
Pages (from-to)	e245-e248
Journal	Pediatrics
Volume	115
Issue number	2
DOIs	https://doi.org/10.1542/peds.2004-1536
State	Published - Feb 2005
Externally published	Yes

Keywords

Aromatase inhibitor
Bone mineral density
Growth hormone
Hormonal control
Short stature

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

Access to Document

10.1542/peds.2004-1536

Cite this

@article{5c7e70a2b7964eee986c96af6608eac5,

title = "Letrozole significantly improves growth potential in a pubertal boy with growth hormone deficiency",

abstract = "Clinical experience with using an aromatase inhibitor to suppress estrogen production during puberty for improvement of growth potential in adolescents with short stature is limited. This report documents treatment of such a patient with a combination of growth hormone and letrozole, a third-generation aromatase inhibitor. Our case demonstrates a favorable outcome on a short-term basis.",

keywords = "Aromatase inhibitor, Bone mineral density, Growth hormone, Hormonal control, Short stature",

author = "Ping Zhou and Bina Shah and Kris Prasad and Raphael David",

year = "2005",

month = feb,

doi = "10.1542/peds.2004-1536",

language = "English (US)",

volume = "115",

pages = "e245--e248",

journal = "Pediatrics",

issn = "0031-4005",

publisher = "American Academy of Pediatrics",

number = "2",

}

TY - JOUR

T1 - Letrozole significantly improves growth potential in a pubertal boy with growth hormone deficiency

AU - Zhou, Ping

AU - Shah, Bina

AU - Prasad, Kris

AU - David, Raphael

PY - 2005/2

Y1 - 2005/2

N2 - Clinical experience with using an aromatase inhibitor to suppress estrogen production during puberty for improvement of growth potential in adolescents with short stature is limited. This report documents treatment of such a patient with a combination of growth hormone and letrozole, a third-generation aromatase inhibitor. Our case demonstrates a favorable outcome on a short-term basis.

AB - Clinical experience with using an aromatase inhibitor to suppress estrogen production during puberty for improvement of growth potential in adolescents with short stature is limited. This report documents treatment of such a patient with a combination of growth hormone and letrozole, a third-generation aromatase inhibitor. Our case demonstrates a favorable outcome on a short-term basis.

KW - Aromatase inhibitor

KW - Bone mineral density

KW - Growth hormone

KW - Hormonal control

KW - Short stature

UR - http://www.scopus.com/inward/record.url?scp=17844393677&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=17844393677&partnerID=8YFLogxK

U2 - 10.1542/peds.2004-1536

DO - 10.1542/peds.2004-1536

M3 - Article

C2 - 15653791

AN - SCOPUS:17844393677

SN - 0031-4005

VL - 115

SP - e245-e248

JO - Pediatrics

JF - Pediatrics

IS - 2

ER -

Letrozole significantly improves growth potential in a pubertal boy with growth hormone deficiency

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this