Left atrial appendage closure devices

Jorge Rromero, Iirving E. Perez, Andrew K. Krumerman, Mario J. Garcia, Richard J. Lucariello

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Atrial fibrillation (AF) increases the risk for thromboembolic stroke five-fold. The left atrial appendage (LAA) has been shown to be the main source of thrombus formation in the majority of strokes associated with AF. Oral anticoagulation with warfarin and novel anticoagu-lants remains the standard of care; however, it has several limitations, including bleeding and poor compliance. Occlusion of the LAA has been shown to be an alternative therapeutic approach to drug therapy. The purpose of this article is to review the different techniques and devices that have emerged for the purpose of occluding this structure, with a particular emphasis on the efficacy and safety studies published to date in the medical literature.

Original languageEnglish (US)
Pages (from-to)45-52
Number of pages8
JournalClinical Medicine Insights: Cardiology
Volume8
DOIs
StatePublished - 2014

Fingerprint

Atrial Appendage
Atrial Fibrillation
Stroke
Equipment and Supplies
Warfarin
Standard of Care
Thrombosis
Hemorrhage
Safety
Drug Therapy
Therapeutics

Keywords

  • Atrial appendage
  • Atrial fibrillation
  • Atrium closure devices
  • LAA

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Left atrial appendage closure devices. / Rromero, Jorge; Perez, Iirving E.; Krumerman, Andrew K.; Garcia, Mario J.; Lucariello, Richard J.

In: Clinical Medicine Insights: Cardiology, Vol. 8, 2014, p. 45-52.

Research output: Contribution to journalArticle

@article{4b1ec6b2ed9b4ab4821e739f20e6f7ca,
title = "Left atrial appendage closure devices",
abstract = "Atrial fibrillation (AF) increases the risk for thromboembolic stroke five-fold. The left atrial appendage (LAA) has been shown to be the main source of thrombus formation in the majority of strokes associated with AF. Oral anticoagulation with warfarin and novel anticoagu-lants remains the standard of care; however, it has several limitations, including bleeding and poor compliance. Occlusion of the LAA has been shown to be an alternative therapeutic approach to drug therapy. The purpose of this article is to review the different techniques and devices that have emerged for the purpose of occluding this structure, with a particular emphasis on the efficacy and safety studies published to date in the medical literature.",
keywords = "Atrial appendage, Atrial fibrillation, Atrium closure devices, LAA",
author = "Jorge Rromero and Perez, {Iirving E.} and Krumerman, {Andrew K.} and Garcia, {Mario J.} and Lucariello, {Richard J.}",
year = "2014",
doi = "10.4137/CMC.S14043",
language = "English (US)",
volume = "8",
pages = "45--52",
journal = "Clinical Medicine Insights: Cardiology",
issn = "1179-5468",
publisher = "Libertas Academica Ltd.",

}

TY - JOUR

T1 - Left atrial appendage closure devices

AU - Rromero, Jorge

AU - Perez, Iirving E.

AU - Krumerman, Andrew K.

AU - Garcia, Mario J.

AU - Lucariello, Richard J.

PY - 2014

Y1 - 2014

N2 - Atrial fibrillation (AF) increases the risk for thromboembolic stroke five-fold. The left atrial appendage (LAA) has been shown to be the main source of thrombus formation in the majority of strokes associated with AF. Oral anticoagulation with warfarin and novel anticoagu-lants remains the standard of care; however, it has several limitations, including bleeding and poor compliance. Occlusion of the LAA has been shown to be an alternative therapeutic approach to drug therapy. The purpose of this article is to review the different techniques and devices that have emerged for the purpose of occluding this structure, with a particular emphasis on the efficacy and safety studies published to date in the medical literature.

AB - Atrial fibrillation (AF) increases the risk for thromboembolic stroke five-fold. The left atrial appendage (LAA) has been shown to be the main source of thrombus formation in the majority of strokes associated with AF. Oral anticoagulation with warfarin and novel anticoagu-lants remains the standard of care; however, it has several limitations, including bleeding and poor compliance. Occlusion of the LAA has been shown to be an alternative therapeutic approach to drug therapy. The purpose of this article is to review the different techniques and devices that have emerged for the purpose of occluding this structure, with a particular emphasis on the efficacy and safety studies published to date in the medical literature.

KW - Atrial appendage

KW - Atrial fibrillation

KW - Atrium closure devices

KW - LAA

UR - http://www.scopus.com/inward/record.url?scp=84902314360&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84902314360&partnerID=8YFLogxK

U2 - 10.4137/CMC.S14043

DO - 10.4137/CMC.S14043

M3 - Article

VL - 8

SP - 45

EP - 52

JO - Clinical Medicine Insights: Cardiology

JF - Clinical Medicine Insights: Cardiology

SN - 1179-5468

ER -