Late motor involvement in cases presenting as 'chronic sensory demyelinating polyneuropathy'

A. R. Berger, Steven Herskovitz, J. Kaplan

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

Chronic inflammatory demyelinating polyneuropathy (CIDP) is usually characterized by prominent motor deficits. A pure sensory presentation, labeled chronic sensory demyelinating neuropathy (CSDN), has been reported, but it is unclear if this neuropathy is a distinct clinical and immunologic entity or merely the sensory presentation of the more usual sensorimotor CIDP. We describe 5 patients with what initially appeared to be CSDN; 3 subsequently developed substantial weakness coincident with the electrophysiologic appearance of multifocal motor conduction block. These cases indicate that, in some cases, CSDN may be a transitional clinical stage of CIDP in which the more usual sensorimotor deficits develop later. Immune- based therapy, including intravenous immunoglobulin, was found to be effective in both the pure sensory and sensorimotor types.

Original languageEnglish (US)
Pages (from-to)440-444
Number of pages5
JournalMuscle and Nerve
Volume18
Issue number4
DOIs
StatePublished - 1995

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Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Polyneuropathies
Intravenous Immunoglobulins
Therapeutics

Keywords

  • chronic inflammatory demyelinating polyneuropathy
  • chronic sensory demyelinating polyneuropathy
  • electrophysiology
  • immunoglobulin
  • sensory neuropathy

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Late motor involvement in cases presenting as 'chronic sensory demyelinating polyneuropathy'. / Berger, A. R.; Herskovitz, Steven; Kaplan, J.

In: Muscle and Nerve, Vol. 18, No. 4, 1995, p. 440-444.

Research output: Contribution to journalArticle

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