Kaposiform hemangioendothelioma with Kasabach-Merritt syndrome mistaken for child abuse in a newborn

Amanda A. Cyrulnik, Manju C. Dawkins, Gert J. Smalberger, Scott Young, Ranon E. Mann, Mark I. Jacobson, Adam J. Friedman

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Kaposiform hemangioendothelioma is a rare vascular neoplasm of childhood that may have an alarming and potentially misleading clinical presentation. Awareness of this entity is important to provide appropriate and immediate medical care. We report the case of a 24-day-old female newborn who presented with a large bruiselike lesion on the left leg. A diagnosis of cellulitis suspected to be secondary to child abuse was made and the patient subsequently was placed in foster care; however, the lesion did not resolve after treatment and relocation. On reevaluation at our institution, physical examination revealed a round, 3 x 4-cm, violaceous, indurated, fixed, nonblanching, nontender plaque with an ivory center and peripheral erythema over the anteromedial aspect of the left leg. Biopsy demonstrated a vascular neoplasm consistent with kaposiform hemangioendothelioma (KHE), and laboratory evaluation revealed thrombocytopenia, low fibrinogen levels, and elevated D-dimer levels, confirming a diagnosis of Kasabach-Merritt syndrome (KMS).

Original languageEnglish (US)
Pages (from-to)E17-E20
JournalCutis
Volume93
Issue number3
StatePublished - Mar 1 2014
Externally publishedYes

Fingerprint

Kasabach-Merritt Syndrome
Vascular Neoplasms
Child Abuse
Leg
Newborn Infant
Cellulitis
Erythema
Thrombocytopenia
Fibrinogen
Physical Examination
Biopsy
Kaposiform Hemangioendothelioma
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Cyrulnik, A. A., Dawkins, M. C., Smalberger, G. J., Young, S., Mann, R. E., Jacobson, M. I., & Friedman, A. J. (2014). Kaposiform hemangioendothelioma with Kasabach-Merritt syndrome mistaken for child abuse in a newborn. Cutis, 93(3), E17-E20.

Kaposiform hemangioendothelioma with Kasabach-Merritt syndrome mistaken for child abuse in a newborn. / Cyrulnik, Amanda A.; Dawkins, Manju C.; Smalberger, Gert J.; Young, Scott; Mann, Ranon E.; Jacobson, Mark I.; Friedman, Adam J.

In: Cutis, Vol. 93, No. 3, 01.03.2014, p. E17-E20.

Research output: Contribution to journalArticle

Cyrulnik, AA, Dawkins, MC, Smalberger, GJ, Young, S, Mann, RE, Jacobson, MI & Friedman, AJ 2014, 'Kaposiform hemangioendothelioma with Kasabach-Merritt syndrome mistaken for child abuse in a newborn', Cutis, vol. 93, no. 3, pp. E17-E20.
Cyrulnik AA, Dawkins MC, Smalberger GJ, Young S, Mann RE, Jacobson MI et al. Kaposiform hemangioendothelioma with Kasabach-Merritt syndrome mistaken for child abuse in a newborn. Cutis. 2014 Mar 1;93(3):E17-E20.
Cyrulnik, Amanda A. ; Dawkins, Manju C. ; Smalberger, Gert J. ; Young, Scott ; Mann, Ranon E. ; Jacobson, Mark I. ; Friedman, Adam J. / Kaposiform hemangioendothelioma with Kasabach-Merritt syndrome mistaken for child abuse in a newborn. In: Cutis. 2014 ; Vol. 93, No. 3. pp. E17-E20.
@article{2b68be3f0b4f42bbb909d5f31ddfd690,
title = "Kaposiform hemangioendothelioma with Kasabach-Merritt syndrome mistaken for child abuse in a newborn",
abstract = "Kaposiform hemangioendothelioma is a rare vascular neoplasm of childhood that may have an alarming and potentially misleading clinical presentation. Awareness of this entity is important to provide appropriate and immediate medical care. We report the case of a 24-day-old female newborn who presented with a large bruiselike lesion on the left leg. A diagnosis of cellulitis suspected to be secondary to child abuse was made and the patient subsequently was placed in foster care; however, the lesion did not resolve after treatment and relocation. On reevaluation at our institution, physical examination revealed a round, 3 x 4-cm, violaceous, indurated, fixed, nonblanching, nontender plaque with an ivory center and peripheral erythema over the anteromedial aspect of the left leg. Biopsy demonstrated a vascular neoplasm consistent with kaposiform hemangioendothelioma (KHE), and laboratory evaluation revealed thrombocytopenia, low fibrinogen levels, and elevated D-dimer levels, confirming a diagnosis of Kasabach-Merritt syndrome (KMS).",
author = "Cyrulnik, {Amanda A.} and Dawkins, {Manju C.} and Smalberger, {Gert J.} and Scott Young and Mann, {Ranon E.} and Jacobson, {Mark I.} and Friedman, {Adam J.}",
year = "2014",
month = "3",
day = "1",
language = "English (US)",
volume = "93",
pages = "E17--E20",
journal = "Cutis",
issn = "0011-4162",
publisher = "Quadrant Healthcom Inc.",
number = "3",

}

TY - JOUR

T1 - Kaposiform hemangioendothelioma with Kasabach-Merritt syndrome mistaken for child abuse in a newborn

AU - Cyrulnik, Amanda A.

AU - Dawkins, Manju C.

AU - Smalberger, Gert J.

AU - Young, Scott

AU - Mann, Ranon E.

AU - Jacobson, Mark I.

AU - Friedman, Adam J.

PY - 2014/3/1

Y1 - 2014/3/1

N2 - Kaposiform hemangioendothelioma is a rare vascular neoplasm of childhood that may have an alarming and potentially misleading clinical presentation. Awareness of this entity is important to provide appropriate and immediate medical care. We report the case of a 24-day-old female newborn who presented with a large bruiselike lesion on the left leg. A diagnosis of cellulitis suspected to be secondary to child abuse was made and the patient subsequently was placed in foster care; however, the lesion did not resolve after treatment and relocation. On reevaluation at our institution, physical examination revealed a round, 3 x 4-cm, violaceous, indurated, fixed, nonblanching, nontender plaque with an ivory center and peripheral erythema over the anteromedial aspect of the left leg. Biopsy demonstrated a vascular neoplasm consistent with kaposiform hemangioendothelioma (KHE), and laboratory evaluation revealed thrombocytopenia, low fibrinogen levels, and elevated D-dimer levels, confirming a diagnosis of Kasabach-Merritt syndrome (KMS).

AB - Kaposiform hemangioendothelioma is a rare vascular neoplasm of childhood that may have an alarming and potentially misleading clinical presentation. Awareness of this entity is important to provide appropriate and immediate medical care. We report the case of a 24-day-old female newborn who presented with a large bruiselike lesion on the left leg. A diagnosis of cellulitis suspected to be secondary to child abuse was made and the patient subsequently was placed in foster care; however, the lesion did not resolve after treatment and relocation. On reevaluation at our institution, physical examination revealed a round, 3 x 4-cm, violaceous, indurated, fixed, nonblanching, nontender plaque with an ivory center and peripheral erythema over the anteromedial aspect of the left leg. Biopsy demonstrated a vascular neoplasm consistent with kaposiform hemangioendothelioma (KHE), and laboratory evaluation revealed thrombocytopenia, low fibrinogen levels, and elevated D-dimer levels, confirming a diagnosis of Kasabach-Merritt syndrome (KMS).

UR - http://www.scopus.com/inward/record.url?scp=84912004741&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84912004741&partnerID=8YFLogxK

M3 - Article

VL - 93

SP - E17-E20

JO - Cutis

JF - Cutis

SN - 0011-4162

IS - 3

ER -