It's not over till the last glomerulus forms

Rosemary Thomas; Frederick J. Kaskel

doi:10.1038/ki.2009.181

It's not over till the last glomerulus forms

Rosemary Thomas, Frederick J. Kaskel

Pediatrics

Research output: Contribution to journal › Comment/debate › peer-review

5 Scopus citations

Abstract

The Brenner hypothesis postulated that low birth weight and decreased nephron number at birth are linked to chronic kidney disease and systemic hypertension in adulthood. To date, little is known about the effect of extrauterine growth retardation (EUGR) on adult kidney disease. Bacchetta et al. present novel data using inulin to show a decrease in renal function for premature children with EUGR. The role of protein nutrition and timing in nephrogenesis is discussed.

Original language	English (US)
Pages (from-to)	361-363
Number of pages	3
Journal	Kidney international
Volume	76
Issue number	4
DOIs	https://doi.org/10.1038/ki.2009.181
State	Published - Aug 2009

ASJC Scopus subject areas

Nephrology

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10.1038/ki.2009.181

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title = "It's not over till the last glomerulus forms",

abstract = "The Brenner hypothesis postulated that low birth weight and decreased nephron number at birth are linked to chronic kidney disease and systemic hypertension in adulthood. To date, little is known about the effect of extrauterine growth retardation (EUGR) on adult kidney disease. Bacchetta et al. present novel data using inulin to show a decrease in renal function for premature children with EUGR. The role of protein nutrition and timing in nephrogenesis is discussed.",

author = "Rosemary Thomas and Kaskel, {Frederick J.}",

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AU - Kaskel, Frederick J.

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AB - The Brenner hypothesis postulated that low birth weight and decreased nephron number at birth are linked to chronic kidney disease and systemic hypertension in adulthood. To date, little is known about the effect of extrauterine growth retardation (EUGR) on adult kidney disease. Bacchetta et al. present novel data using inulin to show a decrease in renal function for premature children with EUGR. The role of protein nutrition and timing in nephrogenesis is discussed.

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It's not over till the last glomerulus forms

Abstract

ASJC Scopus subject areas

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