Intrathecal morphine for postoperative analgesia in children after selective dorsal root rhizotomy

M. M. Harris, M. D. Kahana, T. S. Park

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

The authors report their experience with low doses (0.007-0.015 mg/kg), moderate doses (0.016-0.025 mg/kg), and high doses (0.026-0.035 mg/kg) of intrathecal morphine for postoperative analgesia after selective dorsal root rhizotomy surgery in 50 children, aged 3 to 12 years. After closure of the dura, a single dose of preservative-free morphine was injected into the subarachnoid space, and patients were assessed for 48 hours for level of comfort and side effects. The three doses of morphine provided equivalent analgesia and similar side effects. The duration of postoperative analgesia ranged from 3 to 48 hours (mean, 12.2 ± 9.5 h). Common side effects were limited to nausea and vomiting (42%) and mild facial pruritus. No patient experienced late respiratory depression or generalized pruritus. The authors conclude that low doses of intrathecal morphine is as effective as moderate or high doses of morphine for reducing pain in the immediate postoperative period. Intrathecal morphine provides excellent analgesia after selective dorsal rhizotomy.

Original languageEnglish (US)
Pages (from-to)519-522
Number of pages4
JournalNeurosurgery
Volume28
Issue number4
StatePublished - 1991
Externally publishedYes

Fingerprint

Rhizotomy
Spinal Nerve Roots
Analgesia
Morphine
Pruritus
Subarachnoid Space
Postoperative Period
Respiratory Insufficiency
Nausea
Vomiting
Pain

Keywords

  • Analgesics
  • Intrathecal anesthesia
  • Morphine
  • Pediatrics
  • Postoperative pain
  • Rhizotomy

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Intrathecal morphine for postoperative analgesia in children after selective dorsal root rhizotomy. / Harris, M. M.; Kahana, M. D.; Park, T. S.

In: Neurosurgery, Vol. 28, No. 4, 1991, p. 519-522.

Research output: Contribution to journalArticle

Harris, MM, Kahana, MD & Park, TS 1991, 'Intrathecal morphine for postoperative analgesia in children after selective dorsal root rhizotomy', Neurosurgery, vol. 28, no. 4, pp. 519-522.
Harris, M. M. ; Kahana, M. D. ; Park, T. S. / Intrathecal morphine for postoperative analgesia in children after selective dorsal root rhizotomy. In: Neurosurgery. 1991 ; Vol. 28, No. 4. pp. 519-522.
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