Intrapleural chemotherapy with and without surgery in malignant pleural mesothelioma (MPM)

Bilal Piperdi; Dong M. Shin; Roman Perez-Soler

doi:10.1007/0-387-28274-2_42

Intrapleural chemotherapy with and without surgery in malignant pleural mesothelioma (MPM)

Bilal Piperdi, Dong M. Shin, Roman Perez-Soler

Oncology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

Conclusion and Future Directions: Intrapleural delivery is an effective way of delivering chemotherapy in patients with MPM. Intrapleural chemotherapy can be particularly effective early, when the disease is limited to the pleural surface. However, the current data with the adjuvant intrapleural chemotherapy is inconclusive and should not be routinely used except in the setting of clinical trials. Our results with intrapleural L-NDDP are very encouraging and warrant further studies either as a neoadjuvant or an adjuvant to debulking surgery or in combination with intravenous chemotherapy.

Original language	English (US)
Title of host publication	Malignant Mesothelioma
Subtitle of host publication	Advances in Pathogenesis, Diagnosis, and Translational Therapies
Publisher	Springer New York
Pages	631-637
Number of pages	7
ISBN (Print)	0387229493, 9780387229492
DOIs	https://doi.org/10.1007/0-387-28274-2_42
State	Published - 2005

ASJC Scopus subject areas

Medicine(all)

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10.1007/0-387-28274-2_42

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abstract = "Conclusion and Future Directions: Intrapleural delivery is an effective way of delivering chemotherapy in patients with MPM. Intrapleural chemotherapy can be particularly effective early, when the disease is limited to the pleural surface. However, the current data with the adjuvant intrapleural chemotherapy is inconclusive and should not be routinely used except in the setting of clinical trials. Our results with intrapleural L-NDDP are very encouraging and warrant further studies either as a neoadjuvant or an adjuvant to debulking surgery or in combination with intravenous chemotherapy.",

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N2 - Conclusion and Future Directions: Intrapleural delivery is an effective way of delivering chemotherapy in patients with MPM. Intrapleural chemotherapy can be particularly effective early, when the disease is limited to the pleural surface. However, the current data with the adjuvant intrapleural chemotherapy is inconclusive and should not be routinely used except in the setting of clinical trials. Our results with intrapleural L-NDDP are very encouraging and warrant further studies either as a neoadjuvant or an adjuvant to debulking surgery or in combination with intravenous chemotherapy.

AB - Conclusion and Future Directions: Intrapleural delivery is an effective way of delivering chemotherapy in patients with MPM. Intrapleural chemotherapy can be particularly effective early, when the disease is limited to the pleural surface. However, the current data with the adjuvant intrapleural chemotherapy is inconclusive and should not be routinely used except in the setting of clinical trials. Our results with intrapleural L-NDDP are very encouraging and warrant further studies either as a neoadjuvant or an adjuvant to debulking surgery or in combination with intravenous chemotherapy.

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PB - Springer New York

ER -

Intrapleural chemotherapy with and without surgery in malignant pleural mesothelioma (MPM)

Abstract

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