Intestinal and multivisceral transplantation

Tomoaki Kato, Phillip Ruiz, John F. Thompson, Lon B. Eskind, Deborah Weppler, Farrukh A. Khan, Antonio D. Pinna, Jose R. Nery, Andreas G. Tzakis

Research output: Contribution to journalArticle

111 Citations (Scopus)

Abstract

Intestinal transplantation has been gradually instituted in the management of intestinal failure. More than 200 cases including isolated intestinal transplant, liver/intestinal transplant, and multivisceral transplant have been performed worldwide, with 1-year graft and patient survival rates of 66% and 54%, respectively. Indications for the procedure include short bowel syndrome and functional abnormalities secondary to a variety of diseases or conditions. Tacrolimus-based immunosuppression regimens have been used universally with improved outcomes. The major contributors to the morbidity and mortality include rejection, infection, and technical complications. Of those, control of rejection remains the most difficult dilemma and it will be the key to improved patient and graft survival.

Original languageEnglish (US)
Pages (from-to)226-237
Number of pages12
JournalWorld Journal of Surgery
Volume26
Issue number2
DOIs
StatePublished - Feb 2002
Externally publishedYes

Fingerprint

Transplantation
Graft Survival
Transplants
Short Bowel Syndrome
Tacrolimus
Immunosuppression
Survival Rate
Morbidity
Mortality
Liver
Infection

ASJC Scopus subject areas

  • Surgery

Cite this

Kato, T., Ruiz, P., Thompson, J. F., Eskind, L. B., Weppler, D., Khan, F. A., ... Tzakis, A. G. (2002). Intestinal and multivisceral transplantation. World Journal of Surgery, 26(2), 226-237. https://doi.org/10.1007/s00268-001-0210-5

Intestinal and multivisceral transplantation. / Kato, Tomoaki; Ruiz, Phillip; Thompson, John F.; Eskind, Lon B.; Weppler, Deborah; Khan, Farrukh A.; Pinna, Antonio D.; Nery, Jose R.; Tzakis, Andreas G.

In: World Journal of Surgery, Vol. 26, No. 2, 02.2002, p. 226-237.

Research output: Contribution to journalArticle

Kato, T, Ruiz, P, Thompson, JF, Eskind, LB, Weppler, D, Khan, FA, Pinna, AD, Nery, JR & Tzakis, AG 2002, 'Intestinal and multivisceral transplantation', World Journal of Surgery, vol. 26, no. 2, pp. 226-237. https://doi.org/10.1007/s00268-001-0210-5
Kato, Tomoaki ; Ruiz, Phillip ; Thompson, John F. ; Eskind, Lon B. ; Weppler, Deborah ; Khan, Farrukh A. ; Pinna, Antonio D. ; Nery, Jose R. ; Tzakis, Andreas G. / Intestinal and multivisceral transplantation. In: World Journal of Surgery. 2002 ; Vol. 26, No. 2. pp. 226-237.
@article{6d185fa626254148acd763c90a18f814,
title = "Intestinal and multivisceral transplantation",
abstract = "Intestinal transplantation has been gradually instituted in the management of intestinal failure. More than 200 cases including isolated intestinal transplant, liver/intestinal transplant, and multivisceral transplant have been performed worldwide, with 1-year graft and patient survival rates of 66{\%} and 54{\%}, respectively. Indications for the procedure include short bowel syndrome and functional abnormalities secondary to a variety of diseases or conditions. Tacrolimus-based immunosuppression regimens have been used universally with improved outcomes. The major contributors to the morbidity and mortality include rejection, infection, and technical complications. Of those, control of rejection remains the most difficult dilemma and it will be the key to improved patient and graft survival.",
author = "Tomoaki Kato and Phillip Ruiz and Thompson, {John F.} and Eskind, {Lon B.} and Deborah Weppler and Khan, {Farrukh A.} and Pinna, {Antonio D.} and Nery, {Jose R.} and Tzakis, {Andreas G.}",
year = "2002",
month = "2",
doi = "10.1007/s00268-001-0210-5",
language = "English (US)",
volume = "26",
pages = "226--237",
journal = "World Journal of Surgery",
issn = "0364-2313",
publisher = "Springer New York",
number = "2",

}

TY - JOUR

T1 - Intestinal and multivisceral transplantation

AU - Kato, Tomoaki

AU - Ruiz, Phillip

AU - Thompson, John F.

AU - Eskind, Lon B.

AU - Weppler, Deborah

AU - Khan, Farrukh A.

AU - Pinna, Antonio D.

AU - Nery, Jose R.

AU - Tzakis, Andreas G.

PY - 2002/2

Y1 - 2002/2

N2 - Intestinal transplantation has been gradually instituted in the management of intestinal failure. More than 200 cases including isolated intestinal transplant, liver/intestinal transplant, and multivisceral transplant have been performed worldwide, with 1-year graft and patient survival rates of 66% and 54%, respectively. Indications for the procedure include short bowel syndrome and functional abnormalities secondary to a variety of diseases or conditions. Tacrolimus-based immunosuppression regimens have been used universally with improved outcomes. The major contributors to the morbidity and mortality include rejection, infection, and technical complications. Of those, control of rejection remains the most difficult dilemma and it will be the key to improved patient and graft survival.

AB - Intestinal transplantation has been gradually instituted in the management of intestinal failure. More than 200 cases including isolated intestinal transplant, liver/intestinal transplant, and multivisceral transplant have been performed worldwide, with 1-year graft and patient survival rates of 66% and 54%, respectively. Indications for the procedure include short bowel syndrome and functional abnormalities secondary to a variety of diseases or conditions. Tacrolimus-based immunosuppression regimens have been used universally with improved outcomes. The major contributors to the morbidity and mortality include rejection, infection, and technical complications. Of those, control of rejection remains the most difficult dilemma and it will be the key to improved patient and graft survival.

UR - http://www.scopus.com/inward/record.url?scp=0036482336&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036482336&partnerID=8YFLogxK

U2 - 10.1007/s00268-001-0210-5

DO - 10.1007/s00268-001-0210-5

M3 - Article

VL - 26

SP - 226

EP - 237

JO - World Journal of Surgery

JF - World Journal of Surgery

SN - 0364-2313

IS - 2

ER -