Interleukin-8 gene expression in Staphylococcus aureus-infected endothelial cells

Lei Yao, Franklin D. Lowy, Joan W. Berman

Research output: Contribution to journalArticle

52 Scopus citations

Abstract

Interleukin-8 (IL-8) plays a crucial role in the migration of neutrophils to bacterium-infected sites. This study investigated IL-8 induction in Staphylococcus aureus-infected endothelial cells (EC). We observed that S. aureus-infected EC were induced to express both IL-8 mRNA and protein, which can promote transmigration of neutrophils across an EC monolayer.

Original languageEnglish (US)
Pages (from-to)3407-3409
Number of pages3
JournalInfection and immunity
Volume64
Issue number8
DOIs
StatePublished - 1996

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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