Interleukin-8 gene expression in Staphylococcus aureus-infected endothelial cells

Lei Yao, Franklin D. Lowy, Joan W. Berman

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

Interleukin-8 (IL-8) plays a crucial role in the migration of neutrophils to bacterium-infected sites. This study investigated IL-8 induction in Staphylococcus aureus-infected endothelial cells (EC). We observed that S. aureus-infected EC were induced to express both IL-8 mRNA and protein, which can promote transmigration of neutrophils across an EC monolayer.

Original languageEnglish (US)
Pages (from-to)3407-3409
Number of pages3
JournalInfection and Immunity
Volume64
Issue number8
StatePublished - 1996

Fingerprint

Interleukin-8
Staphylococcus aureus
Endothelial Cells
Gene Expression
Neutrophils
Bacteria
Messenger RNA
Proteins

ASJC Scopus subject areas

  • Immunology

Cite this

Interleukin-8 gene expression in Staphylococcus aureus-infected endothelial cells. / Yao, Lei; Lowy, Franklin D.; Berman, Joan W.

In: Infection and Immunity, Vol. 64, No. 8, 1996, p. 3407-3409.

Research output: Contribution to journalArticle

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