Interleukin-8 (IL-8) plays a crucial role in the migration of neutrophils to bacterium-infected sites. This study investigated IL-8 induction in Staphylococcus aureus-infected endothelial cells (EC). We observed that S. aureus-infected EC were induced to express both IL-8 mRNA and protein, which can promote transmigration of neutrophils across an EC monolayer.
|Original language||English (US)|
|Number of pages||3|
|Journal||Infection and Immunity|
|State||Published - Aug 16 1996|
ASJC Scopus subject areas
- Infectious Diseases