Insulinoma

Aarti Mathur; Philip Gorden; Steven K. Libutti

doi:10.1016/j.suc.2009.06.009

Insulinoma

Aarti Mathur, Philip Gorden, Steven K. Libutti

Surgery

Research output: Contribution to journal › Review article › peer-review

88 Scopus citations

Abstract

Insulinoma is a rare neuroendocrine tumor with an incidence of 4 per 1 million persons per year, which may occur as a unifocal sporadic event in patients without an inherited syndrome or as a part of multiple endocrine neoplasia type 1. Key neuroglycopenic and hypoglycemic symptoms in conjunction with biochemical proof establish the diagnosis. Once the diagnosis is established, the insulinoma is preoperatively localized within the pancreas with the goal of surgical excision for cure. This review discusses the historical background, diagnosis, and management of sporadic insulinoma.

Original language	English (US)
Pages (from-to)	1105-1121
Number of pages	17
Journal	Surgical Clinics of North America
Volume	89
Issue number	5
DOIs	https://doi.org/10.1016/j.suc.2009.06.009
State	Published - Oct 2009

Keywords

Insulinoma
Management
Metastatic insulinoma
Pancreatic neuroendocrine tumor
Surgery

ASJC Scopus subject areas

Surgery

Access to Document

10.1016/j.suc.2009.06.009

Cite this

@article{a52bee8ace55471188cbb5f8c9a81458,

title = "Insulinoma",

abstract = "Insulinoma is a rare neuroendocrine tumor with an incidence of 4 per 1 million persons per year, which may occur as a unifocal sporadic event in patients without an inherited syndrome or as a part of multiple endocrine neoplasia type 1. Key neuroglycopenic and hypoglycemic symptoms in conjunction with biochemical proof establish the diagnosis. Once the diagnosis is established, the insulinoma is preoperatively localized within the pancreas with the goal of surgical excision for cure. This review discusses the historical background, diagnosis, and management of sporadic insulinoma.",

keywords = "Insulinoma, Management, Metastatic insulinoma, Pancreatic neuroendocrine tumor, Surgery",

author = "Aarti Mathur and Philip Gorden and Libutti, {Steven K.}",

year = "2009",

month = oct,

doi = "10.1016/j.suc.2009.06.009",

language = "English (US)",

volume = "89",

pages = "1105--1121",

journal = "Surgical Clinics of North America",

issn = "0039-6109",

publisher = "W.B. Saunders Ltd",

number = "5",

}

TY - JOUR

T1 - Insulinoma

AU - Mathur, Aarti

AU - Gorden, Philip

AU - Libutti, Steven K.

PY - 2009/10

Y1 - 2009/10

N2 - Insulinoma is a rare neuroendocrine tumor with an incidence of 4 per 1 million persons per year, which may occur as a unifocal sporadic event in patients without an inherited syndrome or as a part of multiple endocrine neoplasia type 1. Key neuroglycopenic and hypoglycemic symptoms in conjunction with biochemical proof establish the diagnosis. Once the diagnosis is established, the insulinoma is preoperatively localized within the pancreas with the goal of surgical excision for cure. This review discusses the historical background, diagnosis, and management of sporadic insulinoma.

AB - Insulinoma is a rare neuroendocrine tumor with an incidence of 4 per 1 million persons per year, which may occur as a unifocal sporadic event in patients without an inherited syndrome or as a part of multiple endocrine neoplasia type 1. Key neuroglycopenic and hypoglycemic symptoms in conjunction with biochemical proof establish the diagnosis. Once the diagnosis is established, the insulinoma is preoperatively localized within the pancreas with the goal of surgical excision for cure. This review discusses the historical background, diagnosis, and management of sporadic insulinoma.

KW - Insulinoma

KW - Management

KW - Metastatic insulinoma

KW - Pancreatic neuroendocrine tumor

KW - Surgery

UR - http://www.scopus.com/inward/record.url?scp=70349905093&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=70349905093&partnerID=8YFLogxK

U2 - 10.1016/j.suc.2009.06.009

DO - 10.1016/j.suc.2009.06.009

M3 - Review article

C2 - 19836487

AN - SCOPUS:70349905093

SN - 0039-6109

VL - 89

SP - 1105

EP - 1121

JO - Surgical Clinics of North America

JF - Surgical Clinics of North America

IS - 5

ER -

Insulinoma

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this