Insulinoma

Aarti Mathur, Philip Gorden, Steven K. Libutti

Research output: Contribution to journalReview article

53 Scopus citations

Abstract

Insulinoma is a rare neuroendocrine tumor with an incidence of 4 per 1 million persons per year, which may occur as a unifocal sporadic event in patients without an inherited syndrome or as a part of multiple endocrine neoplasia type 1. Key neuroglycopenic and hypoglycemic symptoms in conjunction with biochemical proof establish the diagnosis. Once the diagnosis is established, the insulinoma is preoperatively localized within the pancreas with the goal of surgical excision for cure. This review discusses the historical background, diagnosis, and management of sporadic insulinoma.

Original languageEnglish (US)
Pages (from-to)1105-1121
Number of pages17
JournalSurgical Clinics of North America
Volume89
Issue number5
DOIs
StatePublished - Oct 1 2009

Keywords

  • Insulinoma
  • Management
  • Metastatic insulinoma
  • Pancreatic neuroendocrine tumor
  • Surgery

ASJC Scopus subject areas

  • Surgery

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  • Cite this

    Mathur, A., Gorden, P., & Libutti, S. K. (2009). Insulinoma. Surgical Clinics of North America, 89(5), 1105-1121. https://doi.org/10.1016/j.suc.2009.06.009