Incidence and prevalence of episcleritis and scleritis in Northern California

Grace Honik, Ira G. Wong, David C. Gritz

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

PURPOSE:: To evaluate the incidence and prevalence of episcleritis and scleritis in a large well-defined population in Northern California. METHODS:: Secondary analysis was performed on data from the Northern California Epidemiology of Uveitis Study. The patient database of a large regional health maintenance organization was searched for all patients who potentially experienced ocular inflammatory disease during the 12-month study period. Medical records were reviewed for all potential patients to confirm ocular inflammatory disease and specific diagnosis, establish the time of onset, and collect additional data. Age- and sex-stratified quarterly study population data were used to calculate incidence rates and prevalence ratios. RESULTS:: After reviewing 2011 possible cases, 297 new-onset cases of episcleritis, 39 prior-onset cases of episcleritis, 25 new-onset cases of scleritis, and 8 prior-onset cases of scleritis were confirmed. For episcleritis, the overall incidence was 41.0 per 100,000 person-years and an annual prevalence ratio of 52.6 per 100,000. The overall incidence of scleritis was 3.4 per 100,000 person-years and an annual prevalence ratio of 5.2 per 100,000 persons. For both episcleritis and scleritis, there was a statistically significant increase in eye disease in older patients (P = 0.05 and <0.001, respectively) and for women in comparison with men (P = 0.001 and <0.001, respectively). Patients with scleritis were older than those with episcleritis (P = 0.017). CONCLUSIONS:: This study found that patients with scleritis were older than those with episcleritis and that women had higher rates of both episcleritis and scleritis compared with what men had.

Original languageEnglish (US)
Pages (from-to)1562-1566
Number of pages5
JournalCornea
Volume32
Issue number12
DOIs
Publication statusPublished - Dec 1 2013

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Keywords

  • epidemiology
  • episcleritis
  • scleritis

ASJC Scopus subject areas

  • Ophthalmology

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