Incidence and prevalence of antibody to hepatitis C virus in FDNY first responders before and after work at the World Trade Center disaster site

Mayris P. Webber, Yang Liu, Hillel W. Cohen, Theresa Schwartz, Michael D. Weiden, Kerry Kelly, Viola Ortiz, Rachel Zeig-Owens, Nadia Jaber, Hilary L. Colbeth, David J. Prezant

Research output: Contribution to journalArticle

Abstract

Background: The goals of this study were to assess the impact of work at the World Trade Center (WTC) site in relation to new, post-9/11/2001 (9/11) antibody to hepatitis C Virus (anti-HCV); and, evaluate secular trends in WTC-exposed male Fire Department of New York City (FDNY) Firefighters and Emergency Medical Services (EMS) responders. Methods: FDNY monitors responder health through physical exams and routine blood work. We used descriptive statistics to compare trans-9/11 and post-9/11 incidence and to assess trends in prevalence from 2000 to 2012. Results: Trans-9/11 incidence of new anti-HCV was 0.42 per 100 persons compared with post-9/11 incidence of 0.34 (P = 0.68). Overall seroprevalence was 1.3%; rates declined from 1.79 per 100 to 0.49 per 100 over time (P < 0.0001). Conclusions: Work at the WTC was not associated with new infection. Biennial seroprevalence in responders declined over time, supporting the FDNY decision to discontinue routine annual testing in this cohort.

Original languageEnglish (US)
Pages (from-to)733-740
Number of pages8
JournalAmerican Journal of Industrial Medicine
Volume61
Issue number9
DOIs
StatePublished - Sep 1 2018

Fingerprint

Hepatitis C Antibodies
Disasters
Seroepidemiologic Studies
Incidence
Firefighters
Emergency Medical Services
Health
Infection

Keywords

  • firefighters
  • hepatitis C
  • incidence
  • prevalence
  • World Trade Center

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Incidence and prevalence of antibody to hepatitis C virus in FDNY first responders before and after work at the World Trade Center disaster site. / Webber, Mayris P.; Liu, Yang; Cohen, Hillel W.; Schwartz, Theresa; Weiden, Michael D.; Kelly, Kerry; Ortiz, Viola; Zeig-Owens, Rachel; Jaber, Nadia; Colbeth, Hilary L.; Prezant, David J.

In: American Journal of Industrial Medicine, Vol. 61, No. 9, 01.09.2018, p. 733-740.

Research output: Contribution to journalArticle

Webber, Mayris P. ; Liu, Yang ; Cohen, Hillel W. ; Schwartz, Theresa ; Weiden, Michael D. ; Kelly, Kerry ; Ortiz, Viola ; Zeig-Owens, Rachel ; Jaber, Nadia ; Colbeth, Hilary L. ; Prezant, David J. / Incidence and prevalence of antibody to hepatitis C virus in FDNY first responders before and after work at the World Trade Center disaster site. In: American Journal of Industrial Medicine. 2018 ; Vol. 61, No. 9. pp. 733-740.
@article{70e24a2cb20240459a66ee005c63212c,
title = "Incidence and prevalence of antibody to hepatitis C virus in FDNY first responders before and after work at the World Trade Center disaster site",
abstract = "Background: The goals of this study were to assess the impact of work at the World Trade Center (WTC) site in relation to new, post-9/11/2001 (9/11) antibody to hepatitis C Virus (anti-HCV); and, evaluate secular trends in WTC-exposed male Fire Department of New York City (FDNY) Firefighters and Emergency Medical Services (EMS) responders. Methods: FDNY monitors responder health through physical exams and routine blood work. We used descriptive statistics to compare trans-9/11 and post-9/11 incidence and to assess trends in prevalence from 2000 to 2012. Results: Trans-9/11 incidence of new anti-HCV was 0.42 per 100 persons compared with post-9/11 incidence of 0.34 (P = 0.68). Overall seroprevalence was 1.3{\%}; rates declined from 1.79 per 100 to 0.49 per 100 over time (P < 0.0001). Conclusions: Work at the WTC was not associated with new infection. Biennial seroprevalence in responders declined over time, supporting the FDNY decision to discontinue routine annual testing in this cohort.",
keywords = "firefighters, hepatitis C, incidence, prevalence, World Trade Center",
author = "Webber, {Mayris P.} and Yang Liu and Cohen, {Hillel W.} and Theresa Schwartz and Weiden, {Michael D.} and Kerry Kelly and Viola Ortiz and Rachel Zeig-Owens and Nadia Jaber and Colbeth, {Hilary L.} and Prezant, {David J.}",
year = "2018",
month = "9",
day = "1",
doi = "10.1002/ajim.22871",
language = "English (US)",
volume = "61",
pages = "733--740",
journal = "American Journal of Industrial Medicine",
issn = "0271-3586",
publisher = "Wiley-Liss Inc.",
number = "9",

}

TY - JOUR

T1 - Incidence and prevalence of antibody to hepatitis C virus in FDNY first responders before and after work at the World Trade Center disaster site

AU - Webber, Mayris P.

AU - Liu, Yang

AU - Cohen, Hillel W.

AU - Schwartz, Theresa

AU - Weiden, Michael D.

AU - Kelly, Kerry

AU - Ortiz, Viola

AU - Zeig-Owens, Rachel

AU - Jaber, Nadia

AU - Colbeth, Hilary L.

AU - Prezant, David J.

PY - 2018/9/1

Y1 - 2018/9/1

N2 - Background: The goals of this study were to assess the impact of work at the World Trade Center (WTC) site in relation to new, post-9/11/2001 (9/11) antibody to hepatitis C Virus (anti-HCV); and, evaluate secular trends in WTC-exposed male Fire Department of New York City (FDNY) Firefighters and Emergency Medical Services (EMS) responders. Methods: FDNY monitors responder health through physical exams and routine blood work. We used descriptive statistics to compare trans-9/11 and post-9/11 incidence and to assess trends in prevalence from 2000 to 2012. Results: Trans-9/11 incidence of new anti-HCV was 0.42 per 100 persons compared with post-9/11 incidence of 0.34 (P = 0.68). Overall seroprevalence was 1.3%; rates declined from 1.79 per 100 to 0.49 per 100 over time (P < 0.0001). Conclusions: Work at the WTC was not associated with new infection. Biennial seroprevalence in responders declined over time, supporting the FDNY decision to discontinue routine annual testing in this cohort.

AB - Background: The goals of this study were to assess the impact of work at the World Trade Center (WTC) site in relation to new, post-9/11/2001 (9/11) antibody to hepatitis C Virus (anti-HCV); and, evaluate secular trends in WTC-exposed male Fire Department of New York City (FDNY) Firefighters and Emergency Medical Services (EMS) responders. Methods: FDNY monitors responder health through physical exams and routine blood work. We used descriptive statistics to compare trans-9/11 and post-9/11 incidence and to assess trends in prevalence from 2000 to 2012. Results: Trans-9/11 incidence of new anti-HCV was 0.42 per 100 persons compared with post-9/11 incidence of 0.34 (P = 0.68). Overall seroprevalence was 1.3%; rates declined from 1.79 per 100 to 0.49 per 100 over time (P < 0.0001). Conclusions: Work at the WTC was not associated with new infection. Biennial seroprevalence in responders declined over time, supporting the FDNY decision to discontinue routine annual testing in this cohort.

KW - firefighters

KW - hepatitis C

KW - incidence

KW - prevalence

KW - World Trade Center

UR - http://www.scopus.com/inward/record.url?scp=85051489640&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85051489640&partnerID=8YFLogxK

U2 - 10.1002/ajim.22871

DO - 10.1002/ajim.22871

M3 - Article

VL - 61

SP - 733

EP - 740

JO - American Journal of Industrial Medicine

JF - American Journal of Industrial Medicine

SN - 0271-3586

IS - 9

ER -