Incidence and prevalence of antibody to hepatitis C virus in FDNY first responders before and after work at the World Trade Center disaster site

Mayris P. Webber, Yang Liu, Hillel W. Cohen, Theresa Schwartz, Michael D. Weiden, Kerry Kelly, Viola Ortiz, Rachel Zeig-Owens, Nadia Jaber, Hilary L. Colbeth, David J. Prezant

Research output: Contribution to journalArticle

Abstract

Background: The goals of this study were to assess the impact of work at the World Trade Center (WTC) site in relation to new, post-9/11/2001 (9/11) antibody to hepatitis C Virus (anti-HCV); and, evaluate secular trends in WTC-exposed male Fire Department of New York City (FDNY) Firefighters and Emergency Medical Services (EMS) responders. Methods: FDNY monitors responder health through physical exams and routine blood work. We used descriptive statistics to compare trans-9/11 and post-9/11 incidence and to assess trends in prevalence from 2000 to 2012. Results: Trans-9/11 incidence of new anti-HCV was 0.42 per 100 persons compared with post-9/11 incidence of 0.34 (P = 0.68). Overall seroprevalence was 1.3%; rates declined from 1.79 per 100 to 0.49 per 100 over time (P < 0.0001). Conclusions: Work at the WTC was not associated with new infection. Biennial seroprevalence in responders declined over time, supporting the FDNY decision to discontinue routine annual testing in this cohort.

Original languageEnglish (US)
Pages (from-to)733-740
Number of pages8
JournalAmerican Journal of Industrial Medicine
Volume61
Issue number9
DOIs
StatePublished - Sep 1 2018

Keywords

  • firefighters
  • hepatitis C
  • incidence
  • prevalence
  • World Trade Center

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

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