A case of ectodermal dysplasia and aplastic anemia is presented in which a cell-mediated immunodeficiency led to a fatal pneumocystis carinii infection. Elevated levels of IgG, IgA and IgD were present with normal specific antibody titers. A deficient cell-mediated immunity was documented by low T cell numbers, poor in vitro mitogenic responses, negative skin tests and by the histologic finding at autopsy of thymic dysplasia.
|Original language||English (US)|
|Number of pages||8|
|Journal||Helvetica Paediatrica Acta|
|Publication status||Published - Jul 22 1978|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health