Immediate vs. delayed post-abortal copper T 380A IUD insertion in cases over 12 weeks of gestation

Miriam Cremer, Kimberley A. Bullard, Raegan Mc Donald Mosley, Christine Weiselberg, Michael Molaei, Veronica Lerner, Todd A. Alonzo

Research output: Contribution to journalArticle

41 Scopus citations

Abstract

Background: The intrauterine device (IUD) is a safe, effective, well-tolerated form of contraception. Immediate placement after second-trimester abortion could increase high-tier contraception use in women who are at high risk for unintended pregnancy. Study Design: This randomized controlled trial compared immediate vs. delayed placement of Copper T380A IUD insertion 2-4 weeks after second trimester abortion. The primary outcome analyzed was the percentage of women using a copper T380A IUD 6 months after surgery. Secondary outcomes were percentage of subjects using other high or middle tier contraception, expulsion, infection and repeat pregnancy rates as well as IUD satisfaction. In expectation of a high loss to follow-up at 6 months, 215 subjects were enrolled for a desired sample size of 158 subjects. Results: Contraceptive and pregnancy status at 6 months was known for 159 of 215 subjects. Women randomized to immediate insertion were significantly more likely to have an IUD at 6 months compared to delayed (81.7% vs. 28.4%, p=.003). Relative risk was 11.2 (95% CI 5-26). There were 8 (5.1%) of 159 repeat unintended pregnancies. No women had a repeat pregnancy that had an IUD placed in the operating room. In the as-treated analysis, 64 women in the immediate group received the IUD and 0% had a repeat pregnancy. Of the remaining 95 women, 8 (8.4%) had a repeat pregnancy. This is a statistically significant difference (p=.022). Conclusion: Placing the IUD immediately after the procedure significantly increases the likelihood of use of effective contraception following a second-trimester procedure. Women who have an IUD placed immediately after their procedure may also be less likely to have a subsequent unplanned pregnancy.

Original languageEnglish (US)
Pages (from-to)522-527
Number of pages6
JournalContraception
Volume83
Issue number6
DOIs
StatePublished - Jun 1 2011
Externally publishedYes

Keywords

  • Contraception
  • IUD insertion
  • Second trimester abortion
  • Unplanned pregnancy

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

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    Cremer, M., Bullard, K. A., Mosley, R. M. D., Weiselberg, C., Molaei, M., Lerner, V., & Alonzo, T. A. (2011). Immediate vs. delayed post-abortal copper T 380A IUD insertion in cases over 12 weeks of gestation. Contraception, 83(6), 522-527. https://doi.org/10.1016/j.contraception.2010.10.005