Hypothalamic sensing of fatty acids

Tony K T Lam, Gary J. Schwartz, Luciano Rossetti

Research output: Contribution to journalArticle

328 Citations (Scopus)

Abstract

Selective regions of the brain, including the hypothalamus, are capable of gathering information on the body's nutritional status in order to implement appropriate behavioral and metabolic responses to changes in fuel availability. This review focuses on direct metabolic signaling within the hypothalamus. There is growing evidence supporting the idea that fatty acid metabolism within discrete hypothalamic regions can function as a sensor for nutrient availability that can integrate multiple nutritional and hormonal signals.

Original languageEnglish (US)
Pages (from-to)579-584
Number of pages6
JournalNature Neuroscience
Volume8
Issue number5
DOIs
StatePublished - May 2005

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Hypothalamus
Fatty Acids
Nutritional Status
Food
Brain

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Hypothalamic sensing of fatty acids. / Lam, Tony K T; Schwartz, Gary J.; Rossetti, Luciano.

In: Nature Neuroscience, Vol. 8, No. 5, 05.2005, p. 579-584.

Research output: Contribution to journalArticle

Lam, Tony K T ; Schwartz, Gary J. ; Rossetti, Luciano. / Hypothalamic sensing of fatty acids. In: Nature Neuroscience. 2005 ; Vol. 8, No. 5. pp. 579-584.
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