Hypertensive intracerebral hematoma. An investigation of the initial hemorrhage and rebleeding using chromium Cr 51 labeled erythrocytes

D. J. Herbstein, H. H. Schaumburg

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

Hypertensive intracerebral hematomas were investigated using chromium Cr 51 labeled erythrocytes. Patients underwent erythrocyte labelling shortly after admission following standard techniques for erythrocyte survival time. At postmortem examination the radioisotopic activity of the primary and secondary (Duret) hemorrhages were determined. In 11 patients with hypertensive hematomas no significant activity was found in the primary hematomas, suggesting that bleeding occurred over a short period of time and there was no rebleeding. Duret hemorrhages present in patients comatose on admission contained no significant activity. The findings in the Duret hemorrhages suggest that patients comatose on arrival sustained these lesions as an almost immediate consequence of the initial primary hemorrhage. In two nonhypertensive patients, intracerebral hematomas secondary to a ruptured berry aneurysm and an arteriovenous malformation contained high levels of radioisotopic activity, suggesting a different pathophysiology of bleeding.

Original languageEnglish (US)
Pages (from-to)412-414
Number of pages3
JournalArchives of Neurology
Volume30
Issue number5
StatePublished - 1974

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Chromium
Hematoma
Erythrocytes
Hemorrhage
Coma
Erythrocyte Aging
Ruptured Aneurysm
Arteriovenous Malformations
Intracranial Aneurysm
Autopsy
Admission

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Hypertensive intracerebral hematoma. An investigation of the initial hemorrhage and rebleeding using chromium Cr 51 labeled erythrocytes. / Herbstein, D. J.; Schaumburg, H. H.

In: Archives of Neurology, Vol. 30, No. 5, 1974, p. 412-414.

Research output: Contribution to journalArticle

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