Hypertensive emergency masquerading as phaeochromocytoma: A report of two cases

Raphael Hulkower; Sriram Gubbi; Mimoza Meholli; Ulrich Schubart

doi:10.1136/bcr-2016-217628

Hypertensive emergency masquerading as phaeochromocytoma: A report of two cases

Raphael Hulkower, Sriram Gubbi, Mimoza Meholli, Ulrich Schubart

Medicine

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

We report two cases of patients who were hospitalised for hypertensive emergency. In both cases, laboratory testing during admission revealed elevated normetanephrines in the range of 4-5 times the upper limit of normal using liquid chromatography with mass spectrometry. Imaging studies did not localise any phaeochromocytoma or paraganglioma (PPGL). Repeat biochemical testing after discharge was within normal limits in both cases. These observations suggest that hypertensive emergency should be recognised as a potential cause of 'false-positive' laboratory findings in the diagnostic assessment for PPGL.

Original language	English (US)
Article number	bcr-2016-217628
Journal	BMJ case reports
Volume	2017
DOIs	https://doi.org/10.1136/bcr-2016-217628
State	Published - 2017

Keywords

adrenal disorders
hypertension

ASJC Scopus subject areas

Medicine(all)

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10.1136/bcr-2016-217628

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abstract = "We report two cases of patients who were hospitalised for hypertensive emergency. In both cases, laboratory testing during admission revealed elevated normetanephrines in the range of 4-5 times the upper limit of normal using liquid chromatography with mass spectrometry. Imaging studies did not localise any phaeochromocytoma or paraganglioma (PPGL). Repeat biochemical testing after discharge was within normal limits in both cases. These observations suggest that hypertensive emergency should be recognised as a potential cause of 'false-positive' laboratory findings in the diagnostic assessment for PPGL.",

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AB - We report two cases of patients who were hospitalised for hypertensive emergency. In both cases, laboratory testing during admission revealed elevated normetanephrines in the range of 4-5 times the upper limit of normal using liquid chromatography with mass spectrometry. Imaging studies did not localise any phaeochromocytoma or paraganglioma (PPGL). Repeat biochemical testing after discharge was within normal limits in both cases. These observations suggest that hypertensive emergency should be recognised as a potential cause of 'false-positive' laboratory findings in the diagnostic assessment for PPGL.

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Hypertensive emergency masquerading as phaeochromocytoma: A report of two cases

Abstract

Keywords

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