Abstract
Twenty infants and children with positive serologic tests for the human T-cell lymphotropic virus type III (HTLV-III) were noted to have similar features including growth failure (75%), microcephaly (70%), and craniofacial abnormalities consisting of ocular hypertelorism (50%); prominent box-like appearance of the forehead (75%); flat nasal bridge (70%); mild upward or downward obliquity of the eyes (65%); long palpebral fissures with blue sclerae (60%); short nose with flattened columella and well-formed, triangular philtrum (65%); and patulous lips (60%). These features constitute a new and distinct dysmorphic syndrome, the HTLV-III embryopathy.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 638-640 |
| Number of pages | 3 |
| Journal | American Journal of Diseases of Children |
| Volume | 140 |
| Issue number | 7 |
| DOIs | |
| State | Published - Jul 1986 |
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
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Cite this
Marion, R. W., Hutcheon, R. G., & Rubinstein, A. (1986). Human T-Cell Lymphotropic Virus Type III (HTLV-III) Embryopathy: A New Dysmorphic Syndrome Associated With Intrauterine HTLV-III Infection. American Journal of Diseases of Children, 140(7), 638-640. https://doi.org/10.1001/archpedi.1986.02140210036020