Human immunodeficiency virus and atherosclerosis

Peter M. Farrugia, Richard J. Lucariello, John T. Coppola

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

The advent of highly active antiretroviral therapy has led to a significant decline in the incidence of mortality and progression to AIDS in HIV-infection. With increased life expectancy, HIV-infected individuals are being affected by cardiovascular disease. Research studies have identified an increased prevalence of traditional coronary risk factors in HIV-infected patients. Additional investigations suggest that the virus itself may independently result in atherosclerosis. Further studies have linked the use of highly active antiretroviral therapy to the atherosclerotic processes. These findings suggest the need to reconsider HIV as one of the traditionally accepted risk factors for coronary artery disease, with treatment aimed at prevention of myocardial infarction.

Original languageEnglish (US)
Pages (from-to)211-215
Number of pages5
JournalCardiology in Review
Volume17
Issue number5
DOIs
StatePublished - Sep 2009

Fingerprint

Atherosclerosis
Highly Active Antiretroviral Therapy
HIV
Life Expectancy
HIV Infections
Coronary Artery Disease
Acquired Immunodeficiency Syndrome
Cardiovascular Diseases
Myocardial Infarction
Viruses
Mortality
Incidence
Research
Therapeutics

Keywords

  • Atherosclerosis
  • Cardiac risk factor
  • Highly active antiretroviral therapy (HAART)
  • Human immunodeficiency virus (HIV)
  • Myocardial infarction

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Human immunodeficiency virus and atherosclerosis. / Farrugia, Peter M.; Lucariello, Richard J.; Coppola, John T.

In: Cardiology in Review, Vol. 17, No. 5, 09.2009, p. 211-215.

Research output: Contribution to journalArticle

Farrugia, Peter M. ; Lucariello, Richard J. ; Coppola, John T. / Human immunodeficiency virus and atherosclerosis. In: Cardiology in Review. 2009 ; Vol. 17, No. 5. pp. 211-215.
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