Histoplasma capsulatum

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

The human pathogenHistoplasma capsulatumis a major endemic dimorphic fungi, existing in a mycelial form in the environment and as a yeast during infection. Exposure toH. capsulatumproduces a range of host responses, from asymptomatic infection to rapidly fatal disease. This chapter will review the current knowledge of the microbial characteristics, pathogenesis, epidemiology, clinical manifestations, current diagnostic and therapeutic approaches, and host immunity toH. capsulatum. In particular, the host response is determined by the outcome of the complex interactions between innate immunity, adaptive immunity and H. capsulatumvirulence factors

Original languageEnglish (US)
Title of host publicationImmunology of Fungal Infections
PublisherSpringer Netherlands
Pages409-426
Number of pages18
ISBN (Electronic)9781402054921
ISBN (Print)9781402054914
DOIs
StatePublished - Jan 1 2007

ASJC Scopus subject areas

  • Medicine(all)
  • Immunology and Microbiology(all)

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    Nosanchuk, J. D. (2007). Histoplasma capsulatum. In Immunology of Fungal Infections (pp. 409-426). Springer Netherlands. https://doi.org/10.1007/1-4020-5492-0_18