HELP-Tagging

Tag-Based Genome-Wide Cytosine Methylation Profiling

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

We describe a restriction enzyme-based approach to study cytosine methylation using massively parallel sequencing that balances cost efficiency with comprehensiveness in a way that is suitable for human disease studies of large patient cohorts.

Original languageEnglish (US)
Title of host publicationTag-Based Next Generation Sequencing
PublisherWiley-VCH
Pages299-309
Number of pages11
ISBN (Print)9783527328192
DOIs
StatePublished - Jan 23 2012

Fingerprint

High-Throughput Nucleotide Sequencing
Methylation
Cytosine
Genes
Genome
Costs and Cost Analysis
Enzymes
Costs

Keywords

  • Applications
  • Cytosine methylation profiling
  • Genome-wide
  • HELP-tagging
  • Methods
  • Tag-based

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

HELP-Tagging : Tag-Based Genome-Wide Cytosine Methylation Profiling. / Suzuki, Masako; Greally, John M.

Tag-Based Next Generation Sequencing. Wiley-VCH, 2012. p. 299-309.

Research output: Chapter in Book/Report/Conference proceedingChapter

Suzuki, Masako ; Greally, John M. / HELP-Tagging : Tag-Based Genome-Wide Cytosine Methylation Profiling. Tag-Based Next Generation Sequencing. Wiley-VCH, 2012. pp. 299-309
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