Headache and Facial Pain in Sickle Cell Disease

Angeliki Vgontzas, Larry Charleston, Matthew S. Robbins

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Children and adolescents with sickle cell disease (SCD) have a high prevalence of recurrent headaches (24.0–43.9 %). Acute presentation with headache can be diagnostically challenging, as the clinician must consider evaluation of several potentially devastating conditions including vascular diseases (stroke, hemorrhage, venous sinus thrombosis, moyamoya, posterior reversible encephalopathy syndrome), facial and orbital bone infarcts, dental pain, and osteomyelitis. Patients with SCD and primary headache disorders may benefit from comprehensive headache treatment plans that include abortive therapy, prophylactic therapy, and non-pharmacological modalities. Although there is limited data in adults, those with SCD are at risk for medication overuse headache secondary to frequent opioid use. Addressing headache in patients with SCD may help to reduce their use of opioids and disability and improve pain and quality of life.

Original languageEnglish (US)
Article number20
Pages (from-to)1-10
Number of pages10
JournalCurrent Pain and Headache Reports
Volume20
Issue number3
DOIs
StatePublished - Mar 1 2016

Fingerprint

Facial Pain
Sickle Cell Anemia
Headache
Opioid Analgesics
Secondary Headache Disorders
Posterior Leukoencephalopathy Syndrome
Primary Headache Disorders
Facial Bones
Intracranial Sinus Thrombosis
Pain
Osteomyelitis
Vascular Diseases
Venous Thrombosis
Tooth
Therapeutics
Stroke
Quality of Life
Hemorrhage

Keywords

  • Abortive treatment
  • Facial pain
  • Headache
  • Medication overuse
  • Prophylactic treatment
  • Sickle cell disease

ASJC Scopus subject areas

  • Clinical Neurology
  • Anesthesiology and Pain Medicine

Cite this

Headache and Facial Pain in Sickle Cell Disease. / Vgontzas, Angeliki; Charleston, Larry; Robbins, Matthew S.

In: Current Pain and Headache Reports, Vol. 20, No. 3, 20, 01.03.2016, p. 1-10.

Research output: Contribution to journalArticle

Vgontzas, A, Charleston, L & Robbins, MS 2016, 'Headache and Facial Pain in Sickle Cell Disease', Current Pain and Headache Reports, vol. 20, no. 3, 20, pp. 1-10. https://doi.org/10.1007/s11916-016-0546-z
Vgontzas, Angeliki ; Charleston, Larry ; Robbins, Matthew S. / Headache and Facial Pain in Sickle Cell Disease. In: Current Pain and Headache Reports. 2016 ; Vol. 20, No. 3. pp. 1-10.
@article{9ae3719d8e5b4457bc118ebbbe27a2e9,
title = "Headache and Facial Pain in Sickle Cell Disease",
abstract = "Children and adolescents with sickle cell disease (SCD) have a high prevalence of recurrent headaches (24.0–43.9 {\%}). Acute presentation with headache can be diagnostically challenging, as the clinician must consider evaluation of several potentially devastating conditions including vascular diseases (stroke, hemorrhage, venous sinus thrombosis, moyamoya, posterior reversible encephalopathy syndrome), facial and orbital bone infarcts, dental pain, and osteomyelitis. Patients with SCD and primary headache disorders may benefit from comprehensive headache treatment plans that include abortive therapy, prophylactic therapy, and non-pharmacological modalities. Although there is limited data in adults, those with SCD are at risk for medication overuse headache secondary to frequent opioid use. Addressing headache in patients with SCD may help to reduce their use of opioids and disability and improve pain and quality of life.",
keywords = "Abortive treatment, Facial pain, Headache, Medication overuse, Prophylactic treatment, Sickle cell disease",
author = "Angeliki Vgontzas and Larry Charleston and Robbins, {Matthew S.}",
year = "2016",
month = "3",
day = "1",
doi = "10.1007/s11916-016-0546-z",
language = "English (US)",
volume = "20",
pages = "1--10",
journal = "Current Pain and Headache Reports",
issn = "1531-3433",
publisher = "Current Science, Inc.",
number = "3",

}

TY - JOUR

T1 - Headache and Facial Pain in Sickle Cell Disease

AU - Vgontzas, Angeliki

AU - Charleston, Larry

AU - Robbins, Matthew S.

PY - 2016/3/1

Y1 - 2016/3/1

N2 - Children and adolescents with sickle cell disease (SCD) have a high prevalence of recurrent headaches (24.0–43.9 %). Acute presentation with headache can be diagnostically challenging, as the clinician must consider evaluation of several potentially devastating conditions including vascular diseases (stroke, hemorrhage, venous sinus thrombosis, moyamoya, posterior reversible encephalopathy syndrome), facial and orbital bone infarcts, dental pain, and osteomyelitis. Patients with SCD and primary headache disorders may benefit from comprehensive headache treatment plans that include abortive therapy, prophylactic therapy, and non-pharmacological modalities. Although there is limited data in adults, those with SCD are at risk for medication overuse headache secondary to frequent opioid use. Addressing headache in patients with SCD may help to reduce their use of opioids and disability and improve pain and quality of life.

AB - Children and adolescents with sickle cell disease (SCD) have a high prevalence of recurrent headaches (24.0–43.9 %). Acute presentation with headache can be diagnostically challenging, as the clinician must consider evaluation of several potentially devastating conditions including vascular diseases (stroke, hemorrhage, venous sinus thrombosis, moyamoya, posterior reversible encephalopathy syndrome), facial and orbital bone infarcts, dental pain, and osteomyelitis. Patients with SCD and primary headache disorders may benefit from comprehensive headache treatment plans that include abortive therapy, prophylactic therapy, and non-pharmacological modalities. Although there is limited data in adults, those with SCD are at risk for medication overuse headache secondary to frequent opioid use. Addressing headache in patients with SCD may help to reduce their use of opioids and disability and improve pain and quality of life.

KW - Abortive treatment

KW - Facial pain

KW - Headache

KW - Medication overuse

KW - Prophylactic treatment

KW - Sickle cell disease

UR - http://www.scopus.com/inward/record.url?scp=84958252461&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84958252461&partnerID=8YFLogxK

U2 - 10.1007/s11916-016-0546-z

DO - 10.1007/s11916-016-0546-z

M3 - Article

C2 - 26879878

AN - SCOPUS:84958252461

VL - 20

SP - 1

EP - 10

JO - Current Pain and Headache Reports

JF - Current Pain and Headache Reports

SN - 1531-3433

IS - 3

M1 - 20

ER -